Sonomechanics Blog

Industrial ultrasonic processors are vital tools for applications like nano-emulsification, cell lysis, nanoparticle dispersion, and nano-crystallization—processes that are widely utilized across numerous industries. Choosing the right system is crucial for achieving superior results and ensuring uninterrupted production, at large volumes on the plant floor.

In this blog post, we will explore the key features that drive performance, helping you make an informed decision and ensuring your ultrasonic processor meets the specific demands of your application.

We are thrilled to announce that Industrial Sonomechanics (ISM) has been granted a new patent by the United States Patent and Trademark Office!

This achievement marks a significant expansion of ISM's intellectual property portfolio. The patent specifically covers several new embodiments of our groundbreaking high-amplitude Barbell Horns® technology, which are crucial to the superior performance and efficiency of our ultrasonic processors.

Further details on our Barbell Horn designs and the new patent are provided below.

The demand for water-soluble mushroom extracts is surging, driven by the growing interest in their therapeutic, health-promoting benefits. Water-soluble extracts are highly desirable due to their enhanced, rapid absorption and ease of incorporation into various consumer products such as beverages, foods, and nutritional supplements [1].

Producing water-soluble mushroom extracts in liquid or powdered forms involves two important processing steps: (1) extraction of the bioactive compounds from mushrooms and (2) their subsequent nano-emulsification to achieve aqueous solubility. Industrial Sonomechanics (ISM) has perfected these processes to ensure that our customers can manufacture the highest-quality finished products infused with water-soluble mushroom extracts. 

Industrial Sonomechanics® (ISM) has recently completed a groundbreaking pre-clinical pharmacokinetic study, comparing two orally administered Δ8-THC nanoemulsions (liquid and powdered) with a Δ8-THC solution in MCT oil. The results demonstrate considerable advantages of nanoemulsions produced with ISM's ultrasonic equipment and NanoStabilizers®, and are detailed in our latest manuscript, currently in press at AAPS PharmSciTech, an official journal of The American Association of Pharmaceutical Scientists.

This marks the industry's first pre-clinical study of Δ8-THC nanoemulsions, which was conducted and published in collaboration with Verdient Science, LLC.

As the curtains closed on the highly anticipated 2023 MJBizCon in Las Vegas, we are excited to share the highlights and emerging trends that took center stage at our booth.

ISM's conference presence showcased a diverse portfolio of cutting-edge water-soluble liquids and powders, captivating attendees with the extraordinary capabilities of our ultrasonic systems and NanoStabilizers®, and formulation development capabilities.

The event drew a large crowd, and we were delighted to welcome numerous existing and potential clients from well-known food and infused beverage brands to our booth. 

Our experience at the trade show was marked by several groundbreaking pre-clinical study and product launches, as well as innovative updates to our ultrasonic systems, reaffirming our commitment to driving innovation in the industry.

Industrial Sonomechanics (ISM) is proud to announce its breakthrough technology for Ultrasound-Assisted Extraction (UAE). Specifically focused on the most challenging and highest value extraction projects, ISM sets itself apart by combining the ability to deliver high-intensity ultrasound (enjoying a 4x advantage over the nearest competitor) with a scalable process flow (10 - 15 L/min flow rate) that is unique in the industry. ISM's versatile and custom-configured equipment set can be applied to multiple bioactives, botanicals, microorganisms, pharmaceuticals, and other related compounds.

Jeff Meyer, COO of Industrial Sonomechanics, dubs this new specialty line "a beast" when it comes to extraction. Meyer notes “The new ISM ultrasonic system empowers companies to swiftly extract a diverse array of botanicals on a large scale, creating a faster ROI for the customer.”

Ultrasound-Assisted Extraction (UAE)—The ISM Difference

ISM’s equipment package enables you to extract active pharmacological agents for drug formulation applications, polyphenols for the food and beverage industry, alkaloid-rich extracts from kratom leaves and mushrooms, as well as cannabinoids and terpenes.

Industrial Sonomechanics (ISM) is thrilled to announce its participation in the upcoming 2023 MJBizCon, set to take place in Las Vegas, NV, this November! We invite you to come and visit us at booth #4629.

Our dedicated team is geared up to showcase a range of advanced technology solutions, including ultrasonic processors, accessories, NanoStabilizer® products, and finished nano-formulations. Don't miss this opportunity to explore our innovations at the biggest cannabis convention of the year!

If you are passionate about formulating and producing your own water-soluble liquid and powdered cannabis, kratom, or other bioactives, be sure to swing by booth #4629. We can't wait to meet you and discuss many exciting possibilities for your projects!

To ensure a dedicated discussion tailored to your needs, we invite you to schedule a meeting with us at your convenience. Reserve your time now by clicking here. 

We are thrilled to announce that Industrial Sonomechanics (ISM) will participate in the 2023 Process Expo in Chicago, IL, this October! Stop by booth #2857, where we will be showcasing our ultrasonic processors and their capabilities in converting plant and mushroom extracts into water-soluble liquids and powders, as well as how they are used for extraction and degassing.

Furthermore, we are delighted to share that ISM's President and Chief Scientific Officer, Dr. Alexey Peshkovsky, will be delivering a keynote presentation entitled "Water-Soluble Cannabinoids and Other Bioactives: Benefits and Production Methods" on Monday, October 23rd, 2023.

Process Expo serves as the ultimate convergence point for all sectors of the food and beverage processing industry, offering a comprehensive showcase of cutting-edge technologies. 

To ensure you make the most of this opportunity, we invite you to schedule a meeting with ISM's team of experts at booth #2857. Reserve your time now by clicking below. We can't wait to connect with you!

Industrial Sonomechanics (ISM) is pleased to announce that the United States Patent and Trademark Office has issued U.S. Patent No. 11,325,094 B2, entitled "Ultrasonic Horn With a Large High-Amplitude Output Surface".

This patent is an extension of our Barbell Horn Ultrasonic Technology (BHUT) intellectual property portfolio that further cements and protects our ultrasonic technology. It represents ISM's commitment to continuous improvement and ongoing equipment R&D.  

The new patent protects several novel features that improve Barbell Horns' ability to provide high vibration amplitudes and large output surface areas simultaneously, circumventing the drawbacks of conventional ultrasonic systems.

We are excited to announce that Industrial Sonomechanics (ISM) will participate in the 2023 New England Cannabis Convention (NECANN) taking place on March 12th, 2023,  in Boston, MA. 

At this event, ISM President and Chief Scientific Officer, Dr. Alexey Peshkovsky, will deliver a keynote presentation entitled: "Water-Soluble" Cannabinoids, Alkaloids and Other Bioactives: Ultrasonic Production of Liquid and Powdered Nano-Formulations."

If you are interested in learning how to formulate and manufacture cannabis, kratom and other bioactives in the form of a water-soluble liquid or powder, please come to Dr. Peshkovsky's talk.