---
title: Using a High-Pressure Homogenizer? Produce Superior Nanoemulsions with All-In-One NanoStabilizers®
description: Compatible with both high-pressure homogenizers (HPH) & ultrasonic processors, NanoStabilizers® ensure the industry’s smallest droplet sizes, superior stability, and rapid onset of action for your nano-formulations.
image: https://blog.sonomechanics.com/hubfs/using%20a%20high%20pressure%20homogenizer.jpg
---

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# Sonomechanics Blog

## [Using a High-Pressure Homogenizer? Produce Superior Nanoemulsions with All-In-One NanoStabilizers®](https://blog.sonomechanics.com/blog/using-a-high-pressure-homogenizer-produce-superior-nanoemulsions-with-all-in-one-nanostabilizers)

 \[fa icon="calendar"\] Feb 12, 2025 7:00:00 AM / by [ISM Team](https://blog.sonomechanics.com/blog/author/ism-team)

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![using a high pressure homogenizer](https://blog.sonomechanics.com/hs-fs/hubfs/using%20a%20high%20pressure%20homogenizer.jpg?width=310&height=310&name=using%20a%20high%20pressure%20homogenizer.jpg)All-In-One [NanoStabilizers](https://sonomechanics.myshopify.com/collections/all-in-one-nanostabilizer)® have transformed the cannabis and nutraceutical industries by simplifying the creation of permanently stable, highly bioavailable nanoemulsions. These revolutionary products are designed to work with a wide range of poorly water-soluble bioactive ingredients, including full- and broad-spectrum oils, distillates, isolates, vitamins, essential oils, terpenes, alkaloids, and many more. Compatible with both high-pressure homogenizers (HPH) and [ultrasonic processors](https://info.sonomechanics.com/ism-ultrasonic-processors-comparison-chart), NanoStabilizers® ensure the industry’s smallest droplet sizes, superior stability, enhanced bioavailability, and rapid onset of action for your nano-formulations.

### **The Science Behind NanoStabilizers®**

NanoStabilizers® are all-in-one, tasteless, food-grade blends of natural (LSO and LSTM) ingredients, designed to pair with high-shear equipment—such as high-pressure homogenizers and ultrasonic processors—to produce readily water-soluble liquid and powdered (LSO, LSTM) nanoemulsions from a wide range of bioactives. These "Science in a Jar" formulations provide elegant, simple, and cost-effective solutions, already enabling thousands of companies to create superior functional products with unmatched quality and performance. Industries benefiting from NanoStabilizers® currently include:

- Pharmaceutical
- Nutraceutical
- Cosmetics
- Food and beverage

### **![](https://lh7-rt.googleusercontent.com/docsz/AD_4nXfvS66sgKyr0E8eL3KnobBtBPRw2Ya6qL9fHMBtHGnACT0bKe6vRu_MQ4RDXqQ1V2MlehdZvky8vKuYo071Fc2U-4g0rlx9TgesJEwUWB5cEmz9aOUFY_gs1X-uro7wcQJH4b0ILw?key=crc0r4GPR6lZ_de79yJA3nzZ)**

### **Tips for Using NanoStabilizers® with HPH Systems **

- **Pre-mix Preparation:** Combine your bioactive ingredient(s), NanoStabilizer®, and water, then pre-homogenize the mixture before processing through the HPH. Typically, a rotor-stator high-shear mixer is required for this step. Refer to your HPH manufacturer’s instructions for specific guidance.
- **Nano-emulsification:** Process the pre-homogenized mixture as you would for a standard emulsion. Follow the recommended operating procedures outlined by your HPH manufacturer.
- **Temperature Control:** Prevent overheating by using the cooling method recommended by your HPH manufacturer during processing.

### **Consider Upgrading to High-Amplitude Ultrasound**

While high-pressure homogenizers provide excellent results with NanoStabilizers®, upgrading to an ultrasonic processor offers distinct advantages:

- **Simplified Processing:**Skip the pre-homogenization step with a rotor-stator high-shear mixer; simple stirring is all that’s needed.![](https://lh7-rt.googleusercontent.com/docsz/AD_4nXcxiGgJNTr2fHtV_SUnww97vSEaIBhVrwXek_IDSoaRmgCrPPV6d5JkNHophTCVsCyj1tCeOwnsgmtTYfp3BXlWaDqWs5k0gnnsALnNAxNFBwS2YVll3wbTX6y7MEcRLCTdlMP2vg?key=crc0r4GPR6lZ_de79yJA3nzZ)
- **Reduced Maintenance Costs**: Avoid costly repairs to critical components and sealing surfaces caused by dissolved gases and entrained air introduced during pre-homogenization.
- **Lower Energy Consumption**: Ultrasonic systems use significantly less energy than HPH systems, reducing operational costs while delivering superior product quality.
- **Effortless Scalability**: ISM’s high-amplitude ultrasonic processors ensure consistent results on [lab](https://www.sonomechanics.com/600_w_laboratory-scale_processor/), [bench](https://www.sonomechanics.com/1200_w_bench-scale_processor/), and [industrial](https://www.sonomechanics.com/3600_w_industrial-scale_processor/) scales, eliminating the need for re-optimization after scale-up.

[![Configure Ultrasonic System  & Get Instant Pricing](https://no-cache.hubspot.com/cta/default/478120/fa07736c-09a5-40db-a5ae-364d315f2543.png)](https://cta-redirect.hubspot.com/cta/redirect/478120/fa07736c-09a5-40db-a5ae-364d315f2543)

### **Get Started with a NanoStabilizer® Starter Kit**

Try our Starter Kit, specially designed for high-pressure homogenizer users, and experience the benefits firsthand.

#### [📧 Contact us](https://info.sonomechanics.com/main-contact-us) [today to learn more](https://info.sonomechanics.com/main-contact-us)! 

![](https://lh7-rt.googleusercontent.com/docsz/AD_4nXeIZ_9Fd6raA3eyTjUhH8-ICTyxtqmhAUzInqi1nfHLUFDheQTveo6c_dKHqbP3XSBhaKcWOLNBnMzMrEjbVOgk8gNY2uUSWT3qmVFOCEwTMDKdFjhG3rKTZHDKKE7CU7Mvi61kIA?key=crc0r4GPR6lZ_de79yJA3nzZ)

 Topics: [Emulsion-based Products](https://blog.sonomechanics.com/blog/topic/emulsion-based-products), [Medical Cannabis](https://blog.sonomechanics.com/blog/topic/medical-cannabis), [Food & Beverage](https://blog.sonomechanics.com/blog/topic/food-beverage)

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#### Written by [ISM Team](https://blog.sonomechanics.com/blog/author/ism-team)

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- [Emulsion-based Products (39)](https://blog.sonomechanics.com/blog/topic/emulsion-based-products)
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### Posts by Topic

- [General Announcements (67)](https://blog.sonomechanics.com/blog/topic/general-announcements)
- [Medical Cannabis (51)](https://blog.sonomechanics.com/blog/topic/medical-cannabis)
- [Emulsion-based Products (39)](https://blog.sonomechanics.com/blog/topic/emulsion-based-products)
- [Ultrasonic Processing Systems (19)](https://blog.sonomechanics.com/blog/topic/ultrasonic-processing-systems)
- [Food & Beverage (15)](https://blog.sonomechanics.com/blog/topic/food-beverage)
- [Process Scale-up (10)](https://blog.sonomechanics.com/blog/topic/process-scale-up)
- [Extraction (7)](https://blog.sonomechanics.com/blog/topic/extraction)
- [Ultrasonic Degassing (7)](https://blog.sonomechanics.com/blog/topic/ultrasonic-degassing)
- [Theory of Ultrasonic Processing (6)](https://blog.sonomechanics.com/blog/topic/theory-of-ultrasonic-processing)
- [Wet Milling and Dispersing (4)](https://blog.sonomechanics.com/blog/topic/wet-milling-and-dispersing)
- [Deaeration (3)](https://blog.sonomechanics.com/blog/topic/deaeration)
- [Liquid Degassing (3)](https://blog.sonomechanics.com/blog/topic/liquid-degassing)
- [Cavitation (1)](https://blog.sonomechanics.com/blog/topic/cavitation)

see all

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