All-In-One NanoStabilizers® have transformed the cannabis and nutraceutical industries by simplifying the creation of permanently stable, highly bioavailable nanoemulsions. These revolutionary products are designed to work with a wide range of poorly water-soluble bioactive ingredients, including full- and broad-spectrum oils, distillates, isolates, vitamins, essential oils, terpenes, alkaloids, and many more. Compatible with both high-pressure homogenizers (HPH) and ultrasonic processors, NanoStabilizers® ensure the industry’s smallest droplet sizes, superior stability, enhanced bioavailability, and rapid onset of action for your nano-formulations.
The Science Behind NanoStabilizers®
NanoStabilizers® are all-in-one, tasteless, food-grade blends of natural (LSO and LSTM) ingredients, designed to pair with high-shear equipment—such as high-pressure homogenizers and ultrasonic processors—to produce readily water-soluble liquid and powdered (LSO, LSTM) nanoemulsions from a wide range of bioactives. These "Science in a Jar" formulations provide elegant, simple, and cost-effective solutions, already enabling thousands of companies to create superior functional products with unmatched quality and performance. Industries benefiting from NanoStabilizers® currently include:
- Pharmaceutical
- Nutraceutical
- Cosmetics
- Food and beverage
Tips for Using NanoStabilizers® with HPH Systems
- Pre-mix Preparation: Combine your bioactive ingredient(s), NanoStabilizer®, and water, then pre-homogenize the mixture before processing through the HPH. Typically, a rotor-stator high-shear mixer is required for this step. Refer to your HPH manufacturer’s instructions for specific guidance.
- Nano-emulsification: Process the pre-homogenized mixture as you would for a standard emulsion. Follow the recommended operating procedures outlined by your HPH manufacturer.
- Temperature Control: Prevent overheating by using the cooling method recommended by your HPH manufacturer during processing.
Consider Upgrading to High-Amplitude Ultrasound
While high-pressure homogenizers provide excellent results with NanoStabilizers®, upgrading to an ultrasonic processor offers distinct advantages:
- Simplified Processing: Skip the pre-homogenization step with a rotor-stator high-shear mixer; simple stirring is all that’s needed.
- Reduced Maintenance Costs: Avoid costly repairs to critical components and sealing surfaces caused by dissolved gases and entrained air introduced during pre-homogenization.
- Lower Energy Consumption: Ultrasonic systems use significantly less energy than HPH systems, reducing operational costs while delivering superior product quality.
- Effortless Scalability: ISM’s high-amplitude ultrasonic processors ensure consistent results on lab, bench, and industrial scales, eliminating the need for re-optimization after scale-up.
Get Started with a NanoStabilizer® Starter Kit
Try our Starter Kit, specially designed for high-pressure homogenizer users, and experience the benefits firsthand.
