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Cannabis Research Publication in the Journal of Drug Delivery Science & Technology

[fa icon="calendar'] Sep 23, 2020 11:45:00 AM / by Iva Gyurgina posted in Emulsion-based Products, General Announcements, Medical Cannabis

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Industrial Sonomechanics® (ISM) is pleased to announce that our peer-reviewed research article, "Cannabis Extract Nanoemulsions Produced by High-intensity Ultrasound: Formulation Development and Scale-up", was recently published in the Journal of Drug Delivery Science and Technology and is now accessible online. The article compares natural and synthetic surfactant-based "water-soluble" CBD nanoemulsion formulations and describes methods used for their optimization and production with scalable Barbell Horn® Ultrasonic Technology (BHUT).

The paper describes two main types of cannabis extract nanoemulsions (natural and synthetic surfactant-based), focusing on formulation optimization procedures, production processes and droplet sizeanalysis techniques used to evaluate the results. ISM's LSP-600 processor configured in the batch-mode was used for the laboratory-scale optimization experiments, after which the process was transferred to the bench scale using our BSP-1200 processor operating in the flow-through mode. Over one million of nano-emulsified 10 mg CBD extract doses were shown to be possible to produce with one BSP-1200 unit per month. This number can be increased by the factor of five by further upgrading to our ISP-3000 processor configured in the flow-through mode.

While not referenced in the article, ISM has since introduced a product called NanoStabilizer®. This all-in-one, tasteless formulation is optimized for the production of translucent nanoemulsions with much smaller droplet sizes than could be achieved prior to its development. 

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Live Webinar: Analysis, Optimization & Production of Translucent Nanoemulsions

[fa icon="calendar'] Aug 24, 2020 10:30:00 AM / by Iva Gyurgina posted in Emulsion-based Products, General Announcements, Medical Cannabis

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Industrial Sonomechanics (ISM) is pleased to invite you to a live webinar, which will be conducted via Zoom at 3:00 pm EST on Thursday, September 10th, 2020. The webinar, entitled "Analysis, Optimization and Production of Translucent Nanoemulsions", will be presented by ISM's Research & Development Scientist, Mr. Shlomo Leibtag, and Micromeritics Instrument Corporation's Global Technical Training and Support Manager and Associate Scientist, Mr. Jack G. Saad. 

Webinar Overview  

Translucent oil-in-water nanoemulsions have become popular for the target site delivery of functional (e.g., biologically active) hydrophobic ingredients and are currently implemented by many industries, including pharmaceutical, cannabis, food & beverage, nutraceutical, chemical, alternative fuel and many more. Driven by their nanoscale (20 - 200 nm) droplet sizes, translucent oil-in-water nanoemulsions have several desirable properties: they are water-compatible, physically and chemically stable, and allow the incorporated hydrophobic ingredients to be delivered rapidly and completely.

But how does one measure nanoemulsion droplet sizes? And how can this information be utilized to optimize nanoemulsion formulations and production parameters?

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Webinar Recording and Q&As: Commercial Production of Water-Soluble THC & CBD

[fa icon="calendar'] Jul 7, 2020 10:00:00 AM / by Iva Gyurgina posted in General Announcements, Medical Cannabis

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The recording of our recent webinar, entitled "Commercial Production of Water-Soluble THC & CBD by High-Intensity Ultrasound", featuring Dr. Alexey Peshkovsky as a speaker, is now ready. The webinar, which was held on Wednesday, May 13th, 2020, had over 400 registered participants and generated close to 200 questions. Some of these questions were addressed by Alexey during the webinar, the answers to the rest are provided in this post. If you have any additional questions, please do not hesitate to contact us or leave a comment below. 

 

 

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Live Webinar: Commercial Production of Water-Soluble THC & CBD by High-Intensity Ultrasound

[fa icon="calendar'] May 5, 2020 2:30:08 PM / by Iva Gyurgina posted in General Announcements, Medical Cannabis

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Industrial Sonomechanics (ISM) is pleased to invite you to a live webinar, which will be conducted via Zoom at 3:00 pm EST on Wednesday, May 13th, 2020. The webinar, entitled "Commercial Production of Water-Soluble THC and CBD Nanoemulsions with High-Intensity Ultrasound", will be presented by ISM's president and Chief Scientific Officer, Dr. Alexey Peshkovsky. If you are interested in producing your own cannabis extract nanoemulsions (water-soluble CBD and THC) that improve cannabinoid absorption and can be offered as tinctures, powders and tablets or infused into beverages, edibles and topicals, please join us for this 1-hour event!

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2020 White Label Expo Highlights: Water-Soluble CBD on the Rise

[fa icon="calendar'] Mar 18, 2020 12:10:33 PM / by Iva Gyurgina posted in General Announcements, Medical Cannabis

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Last month, Industrial Sonomechanics ( ISM ) participated in the 2020 White Label Expo in Las Vegas, NV. This two-day event gathered thousands of exhibitors, speakers and CBD product suppliers under one roof, demonstrating the rapid growth of the cannabis industry. We are excited about the tremendous success of the show and thankful to those of you who were able to join us at our booth and attended Dr. Peshkovsky's presentation.  
 
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ISM will Present at the 2020 White Label USA Expo in Las Vegas, NV

[fa icon="calendar'] Jan 13, 2020 10:30:00 AM / by Iva Gyurgina posted in General Announcements, Medical Cannabis

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Industrial Sonomechanics ( ISMis pleased to announce its participation  in the 2020 White Label USA Expo , taking place in Las Vegas, NV, on February 26 - 27, 2020. If you are interested in producing your own "water-soluble" CBD or THC, please come by our booth #115, where s everal specialists will be available to demonstrate our ultrasonic processors and NanoStabilizer® - an all-in-one blend of tasteless food-grade (GRAS) carrier oils, emulsifiers and preservatives . See how this turn-key technology makes it easy to produce  highly translucent, permanently stable and fully water-compatible  cannabis extract nanoemulsions without having to go through formulation development, processing parameter optimization or any other type of R&D. 
 
At the event, ISM's President and Chief Scientific Officer, Dr. Alexey Peshkovsky, will also deliver a keynote presentation, entitled "Water-Soluble" CBD and THC: Ultrasonic Production of Cannabis Extract Nanoemulsions". 
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Presentation Recording, 2019 Cannabis Drinks Expo, San Francisco, CA

[fa icon="calendar'] Dec 3, 2019 9:30:00 AM / by Iva Gyurgina posted in Emulsion-based Products, General Announcements, Medical Cannabis

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We are happy to announce that the recording of Dr. Alexey Peshkovsky's 2019 Cannabis Drinks Expo keynote presentation is now ready. In his talk, entitled "Water-compatible cannabis extract nanoemulsions: benefits, formulation development and production methodology", ISM President & Chief Scientific Officer covered several topics critical to the cannabis-infused beverage industry.

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ISM will Present at the 2019 CannaCon Expo in Springfield, MA

[fa icon="calendar'] Aug 22, 2019 10:02:56 AM / by Iva Gyurgina posted in General Announcements, Medical Cannabis

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We are happy to announce that Industrial Sonomechanics ( ISM) will participate in the 2019 CannaCon Expo and Conference in Springfield, MA, which will take place on August 23 - 24th, 2019. At the event's seminar, ISM's President and Chief Scientific Officer, Dr. Alexey Peshkovsky, will deliver a presentation entitled "Turn-Key Ultrasonic Technology for the Production of Translucent “Water-Soluble” Cannabis Extract Nanoemulsions"
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ISM will Present at the 2019 USA CBD Expo in Miami, Florida

[fa icon="calendar'] Jul 17, 2019 10:45:02 AM / by Iva Gyurgina posted in General Announcements, Medical Cannabis

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We are happy to announce that Industrial Sonomechanics (ISM) will participate in the 2019 USA CBD Expo in Miami Beach, FL. The event will take place on August 2nd - 4th, 2019, at the Miami Beach Convention Center. At the Expo, ISM's President and Chief Scientific Officer, Dr. Alexey Peshkovsky, will give a talk on how to design and manufacture translucent, permanently stable, fully water-compatible cannabinoid nanoemulsions (aka. water-soluble CBD or THC), which are efficiently absorbed by the body via many convenient administration routes (e.g., as beverages, edibles and topicals).

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ISM will Present at the Cannabis Drinks Expo, San Francisco, July 2019

[fa icon="calendar'] May 31, 2019 9:00:00 AM / by Iva Gyurgina posted in General Announcements

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We are happy to announce that Industrial Sonomechanics (ISM) will participate in the 2019 Cannabis Drinks Expo in San Francisco, CA. The event will take place on July 25th, 2019, at the South San Francisco Conference Center. At the Expo, ISM's President and Chief Scientific Officer, Dr. Alexey Peshkovsky, will give a talk on the benefits, production methodologies, characteristics and administration methods of cannabis extract nanoemulsions (also known as water-soluble CBD and THC), mainly targeting the infused beverage industry. Some of our technology aimed at enabling companies to produce their own cannabis extract and other bio-active ingredient nanoemulsions will also be presented.

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