We are excited to announce that from June 22nd – 26th, 2025 Industrial Sonomechanics (ISM) will be participating in Ultrasonics 2025 – 7th International conference on ultrasonic-based applications: from analysis to synthesis.
On Monday, June 23rd, ISM's president and chief scientific officer, Dr. Alexey Peshkovsky, will speak about scalable ultrasonic manufacturing of nano-formulations for enhanced pharmacokinetic performance of bioactive compounds.
Industrial ultrasonic processors are vital tools for applications like nano-emulsification, cell lysis, nanoparticle dispersion, and nano-crystallization—processes that are widely utilized across numerous industries. Choosing the right system is crucial for achieving superior results and ensuring uninterrupted production, at large volumes on the plant floor.
In this blog post, we will explore the key features that drive performance, helping you make an informed decision and ensuring your ultrasonic processor meets the specific demands of your application.
We are thrilled to announce that Industrial Sonomechanics (ISM) has been granted a new patent by the United States Patent and Trademark Office!
This achievement marks a significant expansion of ISM's intellectual property portfolio. The patent specifically covers several new embodiments of our groundbreaking high-amplitude Barbell Horns® technology, which are crucial to the superior performance and efficiency of our ultrasonic processors.
Further details on our Barbell Horn designs and the new patent are provided below.
Industrial Sonomechanics (ISM) is pleased to announce that the United States Patent and Trademark Office has issued U.S. Patent No. 11,325,094 B2, entitled "Ultrasonic Horn With a Large High-Amplitude Output Surface".
This patent is an extension of our Barbell Horn Ultrasonic Technology (BHUT) intellectual property portfolio that further cements and protects our ultrasonic technology. It represents ISM's commitment to continuous improvement and ongoing equipment R&D.
The new patent protects several novel features that improve Barbell Horns' ability to provide high vibration amplitudes and large output surface areas simultaneously, circumventing the drawbacks of conventional ultrasonic systems.
Industrial Sonomechanics, LLC (ISM) is pleased to announce the commercial availability of its new noise reduction enclosure, NRE-30. This versatile product significantly reduces the noise exposure created by ultrasonic processors in a wide range of configurations while allowing for clear visibility of the enclosed equipment.
The enclosure offers multiple important benefits to users, including a 270-degree view of the workspace and a size that keeps the unit small enough to move around yet sufficiently large to easily fit different types of equipment.
NRE-30 features a strong extruded aluminum frame with durable and transparent plexiglass panels for structural stability, and waterproof sound-absorbing materials for safe and easy clean up. The full-front access door allows for convenient entry, enabling the operator to safely access the equipment inside.
The enclosure is built to accommodate multiple equipment models and configurations, and comes with several sealable inlet/outlet access ports for tubing and cables as well as a support stand and clamping system that fits most ultrasonic processors on the market today.
Industrial Sonomechanics (ISM) has cracked the code in ramping up the power of its high-amplitude industrial-scale ultrasonic liquid processor, increasing the unit's already high 3000 W power rating to 3600 W. The additional power enables our manufacturing customers to improve productivity, thereby increasing the ROI for each process they undertake. It also enables more applications involving viscous liquids (e.g., adhesives, detergents, coatings, food/beverage products), increasing the utility of ISM equipment within more diverse manufacturing conditions.
This comprehensive upgrade also includes Barbell Horn® design improvements, the addition of a storage/mixing tank with magnetically coupled mixer, as well as many enhanced generator features (e.g., intuitive user interface, better overload protection, several new external control/monitoring features), all in a more compact and robust frame.
Recent years have seen major breakthroughs in how vaccines and antiviral drugs are formulated and manufactured. Nanoemulsions and liposomes are now widely used as vaccine and drug carriers because they can easily incorporate lipophilic (in the case of nanoemulsions) and hydrophilic (in the case of liposomes) bioactive compounds, stabilize substances that otherwise undergo hydrolysis, and significantly reduce side effects of potent drugs. For the past 14 years, Industrial Sonomechanics (ISM) has been conducting R&D and supplying its scalable ultrasonic technology to many companies in this field, including those using it in ultrasonic vaccine production and, more recently, in the development of SARS-CoV-
Are you able to make stable emulsions in the lab, but have trouble replicating the same result in the production environment? Scaling up an emulsification process is frequently even more challenging than succeeding at its lab optimization. In most cases, the post-scale-up loss of product stability is caused by the inability of industrial liquid processors to provide the same intensity of shear forces as was implemented during the research phase, which is why choosing the right production-scale equipment is fundamental.