Sonomechanics Blog

Industrial Sonomechanics (ISM) has cracked the code in ramping up the power of its high-amplitude industrial-scale ultrasonic liquid processor, increasing the unit's already high 3000 W power rating to 3600 W. The additional power enables our manufacturing customers to improve productivity, thereby increasing the ROI for each process they undertake. It also enables more applications involving viscous liquids (e.g., adhesives, detergents, coatings, food/beverage products), increasing the utility of ISM equipment within more diverse manufacturing conditions.

This comprehensive upgrade also includes Barbell Horn^® design improvements, the addition of a storage/mixing tank with magnetically coupled mixer, as well as many enhanced generator features (e.g., intuitive user interface, better overload protection, several new external control/monitoring features), all in a more compact and robust frame. 

Recent years have seen major breakthroughs in how vaccines and antiviral drugs are formulated and manufactured. Nanoemulsions and liposomes are now widely used as vaccine and drug carriers because they can easily incorporate lipophilic (in the case of nanoemulsions) and hydrophilic (in the case of liposomes) bioactive compounds, stabilize substances that otherwise undergo hydrolysis, and significantly reduce side effects of potent drugs. For the past 14 years, Industrial Sonomechanics (ISM) has been conducting R&D and supplying its scalable ultrasonic technology to many companies in this field, including those using it in ultrasonic vaccine production and, more recently, in the development of SARS-CoV-2 (novel coronavirus) vaccines and/or treatments of the associated COVID-19 disease. This article describes some of the challenges faced by commercial-scale manufacturers of vaccines and antiviral medications and explains how our technology contributes to overcoming them.  

Are you able to make stable emulsions in the lab, but have trouble replicating the same result in the production environment? Scaling up an emulsification process is frequently even more challenging than succeeding at its lab optimization. In most cases, the post-scale-up loss of product stability is caused by the inability of industrial liquid processors to provide the same intensity of shear forces as was implemented during the research phase, which is why choosing the right production-scale equipment is fundamental.