All-In-One NanoStabilizers® have transformed the cannabis and nutraceutical industries by simplifying the creation of permanently stable, highly bioavailable nanoemulsions. These revolutionary products are designed to work with a wide range of poorly water-soluble bioactive ingredients, including full- and broad-spectrum oils, distillates, isolates, vitamins, essential oils, terpenes, alkaloids, and many more. Compatible with both high-pressure homogenizers (HPH) and ultrasonic processors, NanoStabilizers® ensure the industry’s smallest droplet sizes, superior stability, enhanced bioavailability, and rapid onset of action for your nano-formulations.
Producing fast-acting, highly bioavailable, readily water-soluble nanoemulsions of bioactive ingredients—such as cannabis extracts, pharmaceutical and nutraceutical compounds, vitamins, essential oils, and terpenes—has become standard practice for many functional food and beverage manufacturers. Whether crafting beverages, water-based tinctures, gummies, edibles, or other infused products, the ability to reduce the onset time and enhance the bioavailability of incorporated bioactives is critical. The key to achieving these outcomes lies in formulating nanoemulsions with sub-100 nm median droplet sizes [1, 2].
Industrial Sonomechanics® (ISM) has recently completed a groundbreaking pre-clinical pharmacokinetic study, comparing two orally administered Δ8-THC nanoemulsions (liquid and powdered) with a Δ8-THC solution in MCT oil. The results demonstrate considerable advantages of nanoemulsions produced with ISM's ultrasonic equipment and NanoStabilizers®, and are detailed in our latest manuscript, currently in press at AAPS PharmSciTech, an official journal of The American Association of Pharmaceutical Scientists.
This marks the industry's first pre-clinical study of Δ8-THC nanoemulsions, which was conducted and published in collaboration with Verdient Science, LLC.
We are excited to announce that Industrial Sonomechanics (ISM) will participate in the 2023 New England Cannabis Convention (NECANN) taking place on March 12th, 2023, in Boston, MA.
At this event, ISM President and Chief Scientific Officer, Dr. Alexey Peshkovsky, will deliver a keynote presentation entitled: "Water-Soluble" Cannabinoids, Alkaloids and Other Bioactives: Ultrasonic Production of Liquid and Powdered Nano-Formulations."
If you are interested in learning how to formulate and manufacture cannabis, kratom and other bioactives in the form of a water-soluble liquid or powder, please come to Dr. Peshkovsky's talk.
We are excited to announce that Industrial Sonomechanics (ISM) will participate in the 2022 Wonderland event, taking place on November 3rd - 5th, 2022 in Miami, FL. At this event, ISM's President and Chief Scientific Officer, Dr. Alexey Peshkovsky, will join a panel discussion entitled: "Lab Science Behind the Magic". If you are interested in learning how to extract and formulate bioactive ingredients as water-soluble liquids or powders, please join us at this world's leading psychedelic event.
We are excited to announce that Industrial Sonomechanics (ISM) will participate in the MJBizCon 2022, taking place on November 15 - 18, 2022, in Las Vegas, Nevada.
At this event, our team will be showcasing ultrasonic processors (actually running them!), accessories & spare parts, NanoStabilizer® products and finished nano-formulations, so bring your team and join us at this largest cannabis convention of the year!
If you are interested in formulating and producing your own water-soluble liquid and powdered cannabis, kratom and/or other bioactives, please come see us at Booth 7937.
We are excited to announce that Industrial Sonomechanics (ISM) will participate in the 2022 The Delta 8 + Conversions Expo in Partnership with The CBD Expo, taking place on October 6 - 7, 2022, in Orlando, FL.
At this event, ISM President and Chief Scientific Officer, Dr. Alexey Peshkovsky, will deliver a keynote presentation entitled: "Water-Soluble" Cannabis, Kratom and Other Bioactives: Ultrasonic Production of Liquid and Powdered Nano-Formulations.
If you are interested in learning how to formulate and manufacture cannabis, kratom and other bioactives in the form of a water-soluble liquid or powder, please come to Dr. Peshkovsky's talk.
Benefits include significantly faster throughput, less downtime, and lower total cost of ownership.
Industrial Sonomechanics, LLC (ISM) is happy to announce the commercial availability of several new large-capacity in-line filtration products, which increase the efficiency of the nanoemulsion production process and lower the associated cost.
Filtering is key to nanoemulsion production
Filtration is a necessary post-processing step of ultrasonic nano-emulsification—a process that converts cannabis extracts and/or other hydrophobic bioactives into a water-compatible form. This new integrated unit removes microorganisms (sterilization), dust, titanium particles, and any leftover plant matter while making filtration convenient and highly scalable.
At 1:00 pm EST on June 28th, 2022, please join us for a YouTube podcast with a live Q&A session. This event, entitled "Make and Measure the Potency of Cannabis Extract Nanoemulsions", is a collaboration project between Industrial Sonomechanics (ISM) and Orange Photonics, where Dr. Alexey Peshkovsky (ISM) and Mr. Dylan Wilks (Orange Photonics) will discuss:
1. ISM's ultrasonic technology and NanoStabilizer® formulations used to produce water-soluble cannabis extract nanoemulsions in the forms of translucent liquids, powders, and quick-disintegrating tablets.
2. Principles of Orange Photonics' Light Lab liquid chromatography technology used to measure the potency of liquid and powdered water-soluble cannabis extract nanoemulsions, including detection limits for various cannabinoids.
3. Best ways to prepare samples comprising various nanoemulsion types for accurate cannabinoid content analysis.
4. Typical reasons for and ways to avoid inconsistent or diminishing cannabinoid potency results in nanoemulsions.
5. Benefits of having a Light Lab cannabis analyzer in-house.
We will be chatting with our viewers throughout the presentation. If interested, please join the conversation at 1:00 pm EST on June 28th, 2022!
We are excited to announce that on February 5th, 2022,Industrial Sonomechanics (ISM) will participate in Cannadelic Miami – the World’s First Cannabis & Psychedelics Expo.
At this event, ISM President and Chief Scientific Officer, Dr. Alexey Peshkovsky, will speak about producing water-soluble nano-formulations of cannabis extracts and bioactive alkaloids with increased bioavailability and shortened onset of action.
If you are interested in manufacturing liquid or powdered water-soluble cannabis extracts or other bioactives, please come to Dr. Peshkovsky's talk.