---
title: Sonomechanics Blog | Medical Cannabis
description: Medical Cannabis | High-amplitude, Barbell Horn®-based ultrasonic processors, nano-formulations and more!
---

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# Sonomechanics Blog

[![](https://blog.sonomechanics.com/hubfs/SONOMECHANICS%20water%20soluble%20powders%20and%20liquids.png)](https://blog.sonomechanics.com/blog/how-stable-are-nanoemulsions-made-with-nanostabilizers)

## [How Stable Are Nanoemulsions Made with NanoStabilizer®-LT and NanoStabilizer®-LSO? Here's the Data.](https://blog.sonomechanics.com/blog/how-stable-are-nanoemulsions-made-with-nanostabilizers)

 \[fa icon="calendar'\] Apr 14, 2025, 10:00:00 AM / by [ISM Team](https://blog.sonomechanics.com/blog/author/ism-team) posted in [Emulsion-based Products](https://blog.sonomechanics.com/blog/topic/emulsion-based-products), [Medical Cannabis](https://blog.sonomechanics.com/blog/topic/medical-cannabis), [Food & Beverage](https://blog.sonomechanics.com/blog/topic/food-beverage)

[\[fa icon="comment"\] 2 Comments](https://blog.sonomechanics.com/blog/how-stable-are-nanoemulsions-made-with-nanostabilizers#comments-listing)

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One of the most common questions we receive from customers is about the long-term stability of nanoemulsions made with our [All-In-One NanoStabilizer®](https://sonomechanics.myshopify.com/collections/all-in-one-nanostabilizer) systems—both the liquid (LT) and powdered (LSO) formats—when used with our ultrasonic processors ([lab](https://www.sonomechanics.com/600_w_laboratory-scale_processor/)-, [bench](https://www.sonomechanics.com/1200_w_bench-scale_processor/)-, or[industrial](https://www.sonomechanics.com/3600_w_industrial-scale_processor/)-scale) or third-party high-pressure homogenizers. Specifically, customers want to know how well droplet sizes hold up over time, which is key to maintaining the exceptional pharmacokinetic [performance](https://blog.sonomechanics.com/blog/ism-publishes-a-groundbreaking-pk-study) (high bioavailability and short onset times) these water-soluble formulations are known for.

The answer? Incredibly well.

 

[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/how-stable-are-nanoemulsions-made-with-nanostabilizers)

[![](https://blog.sonomechanics.com/hubfs/using%20a%20high%20pressure%20homogenizer.jpg)](https://blog.sonomechanics.com/blog/using-a-high-pressure-homogenizer-produce-superior-nanoemulsions-with-all-in-one-nanostabilizers)

## [Using a High-Pressure Homogenizer? Produce Superior Nanoemulsions with All-In-One NanoStabilizers®](https://blog.sonomechanics.com/blog/using-a-high-pressure-homogenizer-produce-superior-nanoemulsions-with-all-in-one-nanostabilizers)

 \[fa icon="calendar'\] Feb 12, 2025, 7:00:00 AM / by [ISM Team](https://blog.sonomechanics.com/blog/author/ism-team) posted in [Emulsion-based Products](https://blog.sonomechanics.com/blog/topic/emulsion-based-products), [Medical Cannabis](https://blog.sonomechanics.com/blog/topic/medical-cannabis), [Food & Beverage](https://blog.sonomechanics.com/blog/topic/food-beverage)

[\[fa icon="comment"\] 2 Comments](https://blog.sonomechanics.com/blog/using-a-high-pressure-homogenizer-produce-superior-nanoemulsions-with-all-in-one-nanostabilizers#comments-listing)

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All-In-One [NanoStabilizers](https://sonomechanics.myshopify.com/collections/all-in-one-nanostabilizer)® have transformed the cannabis and nutraceutical industries by simplifying the creation of permanently stable, highly bioavailable nanoemulsions. These revolutionary products are designed to work with a wide range of poorly water-soluble bioactive ingredients, including full- and broad-spectrum oils, distillates, isolates, vitamins, essential oils, terpenes, alkaloids, and many more. Compatible with both high-pressure homogenizers (HPH) and [ultrasonic processors](https://info.sonomechanics.com/ism-ultrasonic-processors-comparison-chart), NanoStabilizers® ensure the industry’s smallest droplet sizes, superior stability, enhanced bioavailability, and rapid onset of action for your nano-formulations.

[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/using-a-high-pressure-homogenizer-produce-superior-nanoemulsions-with-all-in-one-nanostabilizers)

[![](https://blog.sonomechanics.com/hubfs/nanoemulsion%20samples-1.jpg)](https://blog.sonomechanics.com/blog/highly-concentrated-nanoemulsions-with-sub-100-nm-droplets-heres-how-to-make-them)

## [Highly Concentrated Nanoemulsions With Sub-100 nm Droplets: Here’s How to Make Them](https://blog.sonomechanics.com/blog/highly-concentrated-nanoemulsions-with-sub-100-nm-droplets-heres-how-to-make-them)

 \[fa icon="calendar'\] Feb 3, 2025, 1:15:00 AM / by [ISM Team](https://blog.sonomechanics.com/blog/author/ism-team) posted in [Emulsion-based Products](https://blog.sonomechanics.com/blog/topic/emulsion-based-products), [Medical Cannabis](https://blog.sonomechanics.com/blog/topic/medical-cannabis), [Food & Beverage](https://blog.sonomechanics.com/blog/topic/food-beverage)

[\[fa icon="comment"\] 2 Comments](https://blog.sonomechanics.com/blog/highly-concentrated-nanoemulsions-with-sub-100-nm-droplets-heres-how-to-make-them#comments-listing)

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Producing fast-acting, highly bioavailable, readily water-soluble nanoemulsions of bioactive ingredients—such as cannabis extracts, pharmaceutical and [nutraceutical](https://www.sonomechanics.com/nutraceutical/) compounds, vitamins, essential oils, and terpenes—has become standard practice for many functional food and beverage manufacturers. Whether crafting beverages, water-based tinctures, gummies, edibles, or other infused products, the ability to reduce the onset time and enhance the bioavailability of incorporated bioactives is critical. The key to achieving these outcomes lies in formulating nanoemulsions with sub-100 nm median droplet sizes \[1, 2\].

[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/highly-concentrated-nanoemulsions-with-sub-100-nm-droplets-heres-how-to-make-them)

[![](https://blog.sonomechanics.com/hubfs/Copy%20of%20Sonomechanics.com.png)](https://blog.sonomechanics.com/blog/ism-publishes-a-groundbreaking-pk-study)

## [ISM Publishes a Groundbreaking PK Study of Two Δ8-THC Nanoemulsions](https://blog.sonomechanics.com/blog/ism-publishes-a-groundbreaking-pk-study)

 \[fa icon="calendar'\] Dec 19, 2023, 1:00:00 AM / by [ISM Team](https://blog.sonomechanics.com/blog/author/ism-team) posted in [Emulsion-based Products](https://blog.sonomechanics.com/blog/topic/emulsion-based-products), [General Announcements](https://blog.sonomechanics.com/blog/topic/general-announcements), [Medical Cannabis](https://blog.sonomechanics.com/blog/topic/medical-cannabis)

[\[fa icon="comment"\] 0 Comments](https://blog.sonomechanics.com/blog/ism-publishes-a-groundbreaking-pk-study#comments-listing)

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Industrial Sonomechanics® (ISM) has recently completed a groundbreaking pre-clinical pharmacokinetic study, comparing two orally administered **Δ8-THC nanoemulsions** (liquid and powdered) with a **Δ8-THC solution** in MCT oil. The results demonstrate considerable **advantages** of nanoemulsions produced with ISM's ultrasonic [equipment](https://www.sonomechanics.com/3600_w_industrial-scale_processor/?utm_campaign=General%20Announcements&utm_medium=email&_hsmi=284194826&_hsenc=p2ANqtz-8YRCLNqQ7LgthUZOxlQveZrw9Hd8yFp873ednGSsSZJw9iTb9CXiY5_7_NNw6X2WmknGqOWUr9Qkmvur0gDcMRx_wrQw&utm_content=284194826&utm_source=hs_email) and [NanoStabilizers®](https://sonomechanics.myshopify.com/collections/all-in-one-nanostabilizer), and are detailed in our latest [manuscript](https://link.springer.com/epdf/10.1208/s12249-023-02699-1?sharing_token=S5QgmYKAqE_o2kaJ9Md2_pil69fZbNCDjUAQWCaB_PtowdNEYhuEkkxVS5QEajiRP2o9pxo2BOwjC_JFKWcwmEO85yhF9IhYxTyZ7gRmdK8iz-TxIoRsakyO0boVZjRNO1brTpGBgYAMuhOGHmuibg3wR9iIhS5D-nJMlbB00F4=), currently in press at AAPS PharmSciTech, an official journal of The American Association of Pharmaceutical Scientists.

This marks the industry's **first** pre-clinical study of **Δ8-THC nanoemulsions**, which was conducted and published in collaboration with Verdient Science, LLC.

[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/ism-publishes-a-groundbreaking-pk-study)

[![](https://blog.sonomechanics.com/hubfs/Alexey%20Peshkovsky%2c%20Industrial%20Sonomechanics%20at%20NECANN%20Boston.png)](https://blog.sonomechanics.com/blog/ism-presenting-at-2023-necann-boston)

## [ISM Will Be Presenting at the 2023 NECANN in Boston, MA](https://blog.sonomechanics.com/blog/ism-presenting-at-2023-necann-boston)

 \[fa icon="calendar'\] Mar 3, 2023, 1:00:00 PM / by [ISM Team](https://blog.sonomechanics.com/blog/author/ism-team) posted in [Emulsion-based Products](https://blog.sonomechanics.com/blog/topic/emulsion-based-products), [General Announcements](https://blog.sonomechanics.com/blog/topic/general-announcements), [Medical Cannabis](https://blog.sonomechanics.com/blog/topic/medical-cannabis)

[\[fa icon="comment"\] 0 Comments](https://blog.sonomechanics.com/blog/ism-presenting-at-2023-necann-boston#comments-listing)

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We are excited to announce that Industrial Sonomechanics ([ISM](https://www.sonomechanics.com/)) will participate in the 2023 New England Cannabis Convention ([NECANN](https://necann.com/boston/)) taking place on March 12th, 2023,  in Boston, MA. 

At this event, ISM President and Chief Scientific Officer, Dr. Alexey Peshkovsky, will deliver a keynote presentation entitled: *"Water-Soluble" Cannabinoids, Alkaloids and Other Bioactives: Ultrasonic Production of Liquid and Powdered Nano-Formulations."*

If you are interested in learning how to formulate and manufacture cannabis, kratom and other bioactives in the form of a water-soluble liquid or powder, please come to Dr. Peshkovsky's talk. 

[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/ism-presenting-at-2023-necann-boston)

[![](https://blog.sonomechanics.com/hubfs/ogp-wonderland2022.jpg)](https://blog.sonomechanics.com/blog/ism-presenting-at-the-2022-wonderland-miami)

## [ISM Will Be Participating in 2022 Wonderland Event in Miami, FL](https://blog.sonomechanics.com/blog/ism-presenting-at-the-2022-wonderland-miami)

 \[fa icon="calendar'\] Nov 1, 2022, 10:30:00 AM / by [ISM Team](https://blog.sonomechanics.com/blog/author/ism-team) posted in [Emulsion-based Products](https://blog.sonomechanics.com/blog/topic/emulsion-based-products), [General Announcements](https://blog.sonomechanics.com/blog/topic/general-announcements), [Medical Cannabis](https://blog.sonomechanics.com/blog/topic/medical-cannabis)

[\[fa icon="comment"\] 0 Comments](https://blog.sonomechanics.com/blog/ism-presenting-at-the-2022-wonderland-miami#comments-listing)

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<https://microdose.buzz/wonderland/>We are excited to announce that Industrial Sonomechanics ([ISM](https://www.sonomechanics.com/)) will participate in the 2022 [Wonderland](https://microdose.buzz/wonderland/) event, taking place on November 3rd - 5th, 2022 in Miami, FL. At this event, ISM's President and Chief Scientific Officer, Dr. Alexey Peshkovsky, will join a panel discussion entitled: *"Lab Science Behind the Magic"*. If you are interested in learning how to extract and formulate bioactive ingredients as water-soluble liquids or powders, please join us at this world's leading psychedelic event. 

 

[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/ism-presenting-at-the-2022-wonderland-miami)

[![](https://blog.sonomechanics.com/hubfs/MJBizCon%20booth%20sonomechanics%20.jpeg)](https://blog.sonomechanics.com/blog/ism-exhibiting-at-the-2022-mjbizcon)

## [ISM Will Be Exhibiting at the 2022 MJBizCon in Las Vegas](https://blog.sonomechanics.com/blog/ism-exhibiting-at-the-2022-mjbizcon)

 \[fa icon="calendar'\] Oct 21, 2022, 10:30:00 AM / by [ISM Team](https://blog.sonomechanics.com/blog/author/ism-team) posted in [Emulsion-based Products](https://blog.sonomechanics.com/blog/topic/emulsion-based-products), [General Announcements](https://blog.sonomechanics.com/blog/topic/general-announcements), [Medical Cannabis](https://blog.sonomechanics.com/blog/topic/medical-cannabis)

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We are excited to announce that Industrial Sonomechanics ([ISM](https://www.sonomechanics.com/)) will participate in the [MJBizCon 2022](https://mjbizconference.com/), taking place on November 15 - 18, 2022, in Las Vegas, Nevada. 

At this event, our team will be showcasing ultrasonic processors (actually running them!), accessories & spare parts, NanoStabilizer® products and finished nano-formulations, so bring your team and join us at this largest cannabis convention of the year!

If you are interested in formulating and producing your own water-soluble liquid and powdered cannabis, kratom and/or other bioactives, please come see us at Booth 7937. 

[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/ism-exhibiting-at-the-2022-mjbizcon)

[![](https://blog.sonomechanics.com/hubfs/FLORIDA-Speaker-Alexey-Peshkovsky-water-soluble-nanoemulsions.png)](https://blog.sonomechanics.com/blog/ism-presenting-at-the-2022-delta-8-expo)

## [ISM Will Be Presenting at The Delta 8 Expo in Orlando, FL](https://blog.sonomechanics.com/blog/ism-presenting-at-the-2022-delta-8-expo)

 \[fa icon="calendar'\] Sep 29, 2022, 10:30:00 AM / by [ISM Team](https://blog.sonomechanics.com/blog/author/ism-team) posted in [Emulsion-based Products](https://blog.sonomechanics.com/blog/topic/emulsion-based-products), [General Announcements](https://blog.sonomechanics.com/blog/topic/general-announcements), [Medical Cannabis](https://blog.sonomechanics.com/blog/topic/medical-cannabis)

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We are excited to announce that Industrial Sonomechanics ([ISM](https://www.sonomechanics.com/)) will participate in the 2022 The Delta 8 + Conversions Expo in Partnership with The CBD Expo<https://www.cbdexpo.net/>, taking place on October 6 - 7, 2022, in Orlando, FL. 

At this event, ISM President and Chief Scientific Officer, Dr. Alexey Peshkovsky, will deliver a keynote presentation entitled: *"Water-Soluble" Cannabis, Kratom and Other Bioactives: Ultrasonic Production of Liquid and Powdered Nano-Formulations*. 

If you are interested in learning how to formulate and manufacture cannabis, kratom and other bioactives in the form of a water-soluble liquid or powder, please come to Dr. Peshkovsky's talk. 

[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/ism-presenting-at-the-2022-delta-8-expo)

[![](https://blog.sonomechanics.com/hubfs/filtration%20system%20industrial%20sonomechanics.png)](https://blog.sonomechanics.com/blog/new-large-capacity-in-line-filter)

## [ISM Launches Large-Capacity In-Line Cartridge Filter for Nanoemulsions](https://blog.sonomechanics.com/blog/new-large-capacity-in-line-filter)

 \[fa icon="calendar'\] Sep 13, 2022, 10:00:00 AM / by [ISM Team](https://blog.sonomechanics.com/blog/author/ism-team) posted in [Emulsion-based Products](https://blog.sonomechanics.com/blog/topic/emulsion-based-products), [General Announcements](https://blog.sonomechanics.com/blog/topic/general-announcements), [Ultrasonic Processing Systems](https://blog.sonomechanics.com/blog/topic/ultrasonic-processing-systems), [Medical Cannabis](https://blog.sonomechanics.com/blog/topic/medical-cannabis)

[\[fa icon="comment"\] 1 Comment](https://blog.sonomechanics.com/blog/new-large-capacity-in-line-filter#comments-listing)

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#### ***Benefits include significantly faster throughput, less downtime, and lower total cost of ownership.***

Industrial Sonomechanics, LLC ([ISM](https://www.sonomechanics.com/)) is happy to announce the commercial availability of several new large-capacity in-line filtration [products](https://sonomechanics.myshopify.com/collections/in-line-sterilizing-filters), which increase the efficiency of the nanoemulsion production process and lower the associated cost. 

### Filtering is key to nanoemulsion production

[Filtration](https://blog.sonomechanics.com/blog/should-i-filter-my-water-soluble-cannabis-nanoemulsion) is a necessary post-processing step of ultrasonic [nano-emulsification](https://www.sonomechanics.com/production-of-nanoemulsions/)—a process that converts cannabis extracts and/or other hydrophobic bioactives into a water-compatible form. This new integrated unit removes microorganisms (sterilization), dust, titanium particles, and any leftover plant matter while making filtration convenient and highly scalable.

[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/new-large-capacity-in-line-filter)

[![](https://blog.sonomechanics.com/hubfs/podcast%20webinar%20orange%20photonics%20and%20Industrial%20Sonomechanics.png)](https://blog.sonomechanics.com/blog/make-and-measure-potency-of-cannabis-extract-nanoemulsions)

## [Podcast: Make & Measure the Potency of Cannabis Extract Nanoemulsions](https://blog.sonomechanics.com/blog/make-and-measure-potency-of-cannabis-extract-nanoemulsions)

 \[fa icon="calendar'\] Jun 20, 2022, 11:05:50 AM / by [ISM Team](https://blog.sonomechanics.com/blog/author/ism-team) posted in [Emulsion-based Products](https://blog.sonomechanics.com/blog/topic/emulsion-based-products), [General Announcements](https://blog.sonomechanics.com/blog/topic/general-announcements), [Medical Cannabis](https://blog.sonomechanics.com/blog/topic/medical-cannabis)

[\[fa icon="comment"\] 4 Comments](https://blog.sonomechanics.com/blog/make-and-measure-potency-of-cannabis-extract-nanoemulsions#comments-listing)

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<https://youtu.be/v9Z69sQeGCg>

At 1:00 pm EST on June 28th, 2022, please join us for a YouTube [podcast](https://youtu.be/v9Z69sQeGCg) with a live Q&A session. This event, entitled *"Make and Measure the Potency of Cannabis Extract Nanoemulsions",* is a collaboration project between [Industrial Sonomechanics](https://www.sonomechanics.com/) (ISM) and [Orange Photonics](https://www.orangephotonics.com/), where Dr. Alexey Peshkovsky (ISM) and Mr. Dylan Wilks (Orange Photonics) will discuss:

1\. ISM's ultrasonic technology and NanoStabilizer® formulations used to produce water-soluble cannabis extract nanoemulsions in the forms of translucent liquids, powders, and quick-disintegrating tablets.

2\. Principles of Orange Photonics' Light Lab liquid chromatography technology used to measure the potency of liquid and powdered water-soluble cannabis extract nanoemulsions, including detection limits for various cannabinoids.

3\. Best ways to prepare samples comprising various nanoemulsion types for accurate cannabinoid content analysis.

4\. Typical reasons for and ways to avoid inconsistent or diminishing cannabinoid potency results in nanoemulsions.

5\. Benefits of having a Light Lab cannabis analyzer in-house.

We will be chatting with our viewers throughout the presentation. If interested, please join the conversation at 1:00 pm EST on June 28th, 2022!

[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/make-and-measure-potency-of-cannabis-extract-nanoemulsions)

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- [Emulsion-based Products (39)](https://blog.sonomechanics.com/blog/topic/emulsion-based-products)
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- [Ultrasonic Degassing (7)](https://blog.sonomechanics.com/blog/topic/ultrasonic-degassing)
- [Theory of Ultrasonic Processing (6)](https://blog.sonomechanics.com/blog/topic/theory-of-ultrasonic-processing)
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Industrial Sonomechanics is a R&D, equipment design and process consulting firm, specializing in high-power ultrasonic technology for liquid treatment. Our mission is to help businesses implement their ultrasound-assisted processes on lab, pilot and industrial scales.

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