---
title: Sonomechanics Blog (10)
description: High-amplitude, Barbell Horn®-based ultrasonic processors, nano-formulations and more! (10)
---
[.jpg?width=1994&height=332&name=Logo%20Sonomechanics%20White%20No%20Shadow%20R_Final%20(1).jpg "Sonomechanics logo")](http://sonomechanics.com/)
- [Blog](https://blog.sonomechanics.com/blog)
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# Sonomechanics Blog
[](https://blog.sonomechanics.com/blog/celebrating-ten-years-of-industrial-sonomechanics)
## [Celebrating the 10th anniversary of Industrial Sonomechanics!](https://blog.sonomechanics.com/blog/celebrating-ten-years-of-industrial-sonomechanics)
\[fa icon="calendar'\] Aug 7, 2016, 5:36:31 PM / by [Iva Gyurgina](https://blog.sonomechanics.com/blog/author/iva-gyurgina) posted in [General Announcements](https://blog.sonomechanics.com/blog/topic/general-announcements)
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10 years ago Dr. Alexey Peshkovsky quit his job in medical physics and joined his father, Dr. Sergei Peshkovsky, in founding Industrial Sonomechanics, LLC (ISM). This year, with hundreds of clients all around the world, a number of partnerships and long-term R&D contracts, as well as a double-digit billion-dollar market to pursue in several industries, we were happy to celebrate our first double-digit anniversary!
[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/celebrating-ten-years-of-industrial-sonomechanics)
[](https://blog.sonomechanics.com/blog/water-soluble-cbd)
## [Can CBD or THC be Made Water-Soluble?](https://blog.sonomechanics.com/blog/water-soluble-cbd)
\[fa icon="calendar'\] Jul 3, 2016, 10:11:12 AM / by [Alexey Peshkovsky, Ph.D.](https://blog.sonomechanics.com/blog/author/alexey-peshkovsky-ph-d) posted in [Emulsion-based Products](https://blog.sonomechanics.com/blog/topic/emulsion-based-products), [Medical Cannabis](https://blog.sonomechanics.com/blog/topic/medical-cannabis)
[\[fa icon="comment"\] 91 Comments](https://blog.sonomechanics.com/blog/water-soluble-cbd#comments-listing)
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Cannabinoids (CBD, THC, etc.) are hydrophobic (water-hating) oily substances and, as such, not water-**soluble**. They can, however, be formulated to be water-**compatible** and **appear** water-soluble.
The term "water-soluble CBD" has lately been extensively used throughout the medical cannabis industry. "Water-soluble" means able to homogeneously incorporate into water by separating into molecules or ions (**dissolve** like sugar, alcohol or salt). Oily substances, however, are repelled by water, which forces them to stay separate from it.
[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/water-soluble-cbd)
[](https://blog.sonomechanics.com/blog/2016-ultrasonics-presentation-report)
## [Ultrasonics 2016 International Conference Presentation Report](https://blog.sonomechanics.com/blog/2016-ultrasonics-presentation-report)
\[fa icon="calendar'\] Jul 1, 2016, 2:51:06 PM / by [Iva Gyurgina](https://blog.sonomechanics.com/blog/author/iva-gyurgina) posted in [General Announcements](https://blog.sonomechanics.com/blog/topic/general-announcements)
[\[fa icon="comment"\] 0 Comments](https://blog.sonomechanics.com/blog/2016-ultrasonics-presentation-report#comments-listing)
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Last month, Industrial Sonomechanics ( **[ISM](http://www.sonomechanics.com/)**) had a chance to participate in the [**Ultrasonics 2016**](http://www.ultrasonics2016.com/) International Conference, where Dr. Alexey Peshkovsky gave a talk entitled *"High-Intensity Ultrasonic Liquid Processing on Laboratory, Bench and Industrial Scales."*
The congress, which took place in Caprica, Portugal, on June 6th - 8th, 2016, was a very educational and productive experience. A wide variety of topics related to ultrasonics were covered by presenters from industrial, academic and government institutions worldwide. ISM's presentation was part of the Ultrasound and Engineering topic group.
[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/2016-ultrasonics-presentation-report)
[](https://blog.sonomechanics.com/blog/ultrasonic-production-of-nano-cannabinoids)
## [Are Cannabinoids More Effective in Nano Form?](https://blog.sonomechanics.com/blog/ultrasonic-production-of-nano-cannabinoids)
\[fa icon="calendar'\] May 28, 2016, 5:27:08 PM / by [Alexey Peshkovsky, Ph.D.](https://blog.sonomechanics.com/blog/author/alexey-peshkovsky-ph-d) posted in [Emulsion-based Products](https://blog.sonomechanics.com/blog/topic/emulsion-based-products), [Medical Cannabis](https://blog.sonomechanics.com/blog/topic/medical-cannabis)
[\[fa icon="comment"\] 49 Comments](https://blog.sonomechanics.com/blog/ultrasonic-production-of-nano-cannabinoids#comments-listing)
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Medicinal uses of the cannabis plant (e.g., medical marijuana, hemp) have now been legalized in most US states. In addition to terpenoids and flavonoids, the plant may contain over 85 different types of therapeutically active compounds known as *cannabinoids*, the main two of which are tetrahydrocannabinol (THC) and cannabidiol (CBD). In recent years, medications based on concentrated cannabis extracts have become popular because they allow many routes of administration that are preferable to smoking the plant itself.
[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/ultrasonic-production-of-nano-cannabinoids)
[](https://blog.sonomechanics.com/blog/ism-is-presenting-in-portugal)
## [ISM will be presenting at Ultrasonics-2016 conference in Portugal](https://blog.sonomechanics.com/blog/ism-is-presenting-in-portugal)
\[fa icon="calendar'\] May 20, 2016, 1:05:26 PM / by [Iva Gyurgina](https://blog.sonomechanics.com/blog/author/iva-gyurgina) posted in [General Announcements](https://blog.sonomechanics.com/blog/topic/general-announcements)
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We are happy to announce that Industrial Sonomechanics (ISM) will be presenting at the "2nd International Conference on Ultrasonic-Based Applications: From Analysis to Synthesis" (**[ULTRASONICS-2016](http://www.ultrasonics2016.com/)**) in Caparica, Portugal, where [**Dr. Alexey Peshkovsky**](http://sonomechanics.com/about_ism/our_team/) will give a talk, entitled *"High-Intensity Ultrasonic Liquid Processing on Laboratory, Bench and Industrial Scales."*
[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/ism-is-presenting-in-portugal)
[](https://blog.sonomechanics.com/blog/ism-is-moving)
## [ISM is moving to a new location!](https://blog.sonomechanics.com/blog/ism-is-moving)
\[fa icon="calendar'\] May 19, 2016, 7:30:00 AM / by [Iva Gyurgina](https://blog.sonomechanics.com/blog/author/iva-gyurgina) posted in [General Announcements](https://blog.sonomechanics.com/blog/topic/general-announcements)
[\[fa icon="comment"\] 1 Comment](https://blog.sonomechanics.com/blog/ism-is-moving#comments-listing)
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#### We are growing, so we are moving!
On **June 1st, 2016**, Industrial Sonomechanics will relocate to a much larger facility at **560 W 144th Street, Suite 6, New York, NY 10031**. Our phone number will still be the same - 646-580-4676.
[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/ism-is-moving)
[](https://blog.sonomechanics.com/blog/guide-to-disassembling-your-isp-3000-ultrasonic-processor)
## [Disassembling Your ISP-3000 Industrial-Scale Ultrasonic Processor](https://blog.sonomechanics.com/blog/guide-to-disassembling-your-isp-3000-ultrasonic-processor)
\[fa icon="calendar'\] May 1, 2016, 10:04:17 AM / by [Iva Gyurgina](https://blog.sonomechanics.com/blog/author/iva-gyurgina) posted in [Ultrasonic Processing Systems](https://blog.sonomechanics.com/blog/topic/ultrasonic-processing-systems)
[\[fa icon="comment"\] 1 Comment](https://blog.sonomechanics.com/blog/guide-to-disassembling-your-isp-3000-ultrasonic-processor#comments-listing)
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The [**IS**](http://sonomechanics.com/products_services/3000_w_industrial-scale_processor/)**[P-3000](http://sonomechanics.com/products_services/500_w_laboratory-scale_processor/)** ultrasonic processor is supplied mostly pre-assembled and ready-to-use. Knowing how to take it apart can be helpful when you need to replace a part (e.g., Barbell **[horn](http://sonomechanics.com/technology/ultrasonic_horn_designs_and_properties/)**), troubleshoot or clean the processor. In this post, we provide step-by-step disassembly instructions for the ISP-3000 configured in the flow-through mode. A link to the video on this topic is included at the end.
Before you begin, please review the [**user's manual**](http://sonomechanics.com/files/technical_resources/downloads/Manual%20for%20ISP-3000%20Industrial-Scale%20Ultrasonic%20Processor.pdf) and familiarize yourself with the processor's **[components](https://blog.sonomechanics.com/blog/four-terms-you-need-to-understand-about-your-ultrasonic-processor)**.
[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/guide-to-disassembling-your-isp-3000-ultrasonic-processor)
[](https://blog.sonomechanics.com/blog/ultrasonic-pasteurization-of-milk-and-water-based-beverages)
## [Ultrasonic Pasteurization of Milk and Water-Based Beverages](https://blog.sonomechanics.com/blog/ultrasonic-pasteurization-of-milk-and-water-based-beverages)
\[fa icon="calendar'\] Apr 16, 2016, 5:29:03 PM / by [Alexey Peshkovsky, Ph.D.](https://blog.sonomechanics.com/blog/author/alexey-peshkovsky-ph-d) posted in [Food & Beverage](https://blog.sonomechanics.com/blog/topic/food-beverage)
[\[fa icon="comment"\] 16 Comments](https://blog.sonomechanics.com/blog/ultrasonic-pasteurization-of-milk-and-water-based-beverages#comments-listing)
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One of the main challenges in the food & beverage industry is the inactivation of microorganisms (pasteurization). Thermal treatment of such products as milk and fruit-based beverages (generally, at over 70 °C) is currently the most commonly applied pasteurization method. Unfortunately, this approach causes significant deterioration of many of these products' attributes, such as flavor, color and nutritional quality. Alternative, non-thermal pasteurization methods that can not only ensure the microbial safety of the products, but also preserve their quality are, therefore, of great interest to this industry.
[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/ultrasonic-pasteurization-of-milk-and-water-based-beverages)
[](https://blog.sonomechanics.com/blog/acoustic-cavitation-visual-examples)
## [Acoustic Cavitation: Visual Examples of Chemical & Physical Processes](https://blog.sonomechanics.com/blog/acoustic-cavitation-visual-examples)
\[fa icon="calendar'\] Apr 10, 2016, 12:45:02 PM / by [Alexey Peshkovsky, Ph.D.](https://blog.sonomechanics.com/blog/author/alexey-peshkovsky-ph-d) posted in [Theory of Ultrasonic Processing](https://blog.sonomechanics.com/blog/topic/theory-of-ultrasonic-processing)
[\[fa icon="comment"\] 2 Comments](https://blog.sonomechanics.com/blog/acoustic-cavitation-visual-examples#comments-listing)
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In our previous blog post on ultrasonic **[cavitation](https://blog.sonomechanics.com/blog/acoustic-cavitation-the-driving-force-behind-ultrasonic-processing)** in liquids, we described it as a cloud of low-pressure voids (a.k.a., vacuum bubbles or cavities) that grow, briefly oscillate and finally asymmetrically implode with great intensity. This effect causes extreme local temperatures and pressures, which can produce free radicals and give rise to many chemical (sonochemical) reactions. It also generates extremely powerful micro-jets and enormous shear forces, which promote a variety of physical (mechanical) processes. In some instances, these effects can be clearly seen as they occur. In this post, we provide such visual examples of chemical and mechanical processes.
[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/acoustic-cavitation-visual-examples)
[](https://blog.sonomechanics.com/blog/guide-to-assembling-isp-3000-ultrasonic-processor)
## [Assembling Your ISP-3000 Industrial-Scale Ultrasonic Processor](https://blog.sonomechanics.com/blog/guide-to-assembling-isp-3000-ultrasonic-processor)
\[fa icon="calendar'\] Apr 5, 2016, 8:30:00 AM / by [Iva Gyurgina](https://blog.sonomechanics.com/blog/author/iva-gyurgina) posted in [Ultrasonic Processing Systems](https://blog.sonomechanics.com/blog/topic/ultrasonic-processing-systems)
[\[fa icon="comment"\] 5 Comments](https://blog.sonomechanics.com/blog/guide-to-assembling-isp-3000-ultrasonic-processor#comments-listing)
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The **I[SP-3000](http://sonomechanics.com/products_services/3000_w_industrial-scale_processor/)**industrial-scale ultrasonic liquid processor is a Barbell Horn Ultrasonic Technology ([**BHUT**](https://www.youtube.com/watch?v=IAc-glwNAto))-based system designed for high-volume production. It can be implemented in two processing modes:[**flow-through**](http://www.sonomechanics.com/files/ultrasonic_systems/m_recirculating_mode_schematic_isp-3000.jpg) and [**batch**](http://www.sonomechanics.com/files/ultrasonic_systems/m_batch_mode_schematic_isp-3000.jpg).
Although this ultrasonic processor is supplied mostly pre-assembled and ready-to-use, knowing how to put it together can be helpful. In this blog post we provide step-by-step assembly instructions for the ISP-3000 configured in the flow-through mode.
[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/guide-to-assembling-isp-3000-ultrasonic-processor)
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- [General Announcements (69)](https://blog.sonomechanics.com/blog/topic/general-announcements)
- [Medical Cannabis (51)](https://blog.sonomechanics.com/blog/topic/medical-cannabis)
- [Emulsion-based Products (39)](https://blog.sonomechanics.com/blog/topic/emulsion-based-products)
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- [Ultrasonic Degassing (7)](https://blog.sonomechanics.com/blog/topic/ultrasonic-degassing)
- [Theory of Ultrasonic Processing (6)](https://blog.sonomechanics.com/blog/topic/theory-of-ultrasonic-processing)
- [Wet Milling and Dispersing (4)](https://blog.sonomechanics.com/blog/topic/wet-milling-and-dispersing)
- [Deaeration (3)](https://blog.sonomechanics.com/blog/topic/deaeration)
- [Liquid Degassing (3)](https://blog.sonomechanics.com/blog/topic/liquid-degassing)
- [Cavitation (1)](https://blog.sonomechanics.com/blog/topic/cavitation)
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- [General Announcements (69)](https://blog.sonomechanics.com/blog/topic/general-announcements)
- [Medical Cannabis (51)](https://blog.sonomechanics.com/blog/topic/medical-cannabis)
- [Emulsion-based Products (39)](https://blog.sonomechanics.com/blog/topic/emulsion-based-products)
- [Ultrasonic Processing Systems (19)](https://blog.sonomechanics.com/blog/topic/ultrasonic-processing-systems)
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- [Process Scale-up (10)](https://blog.sonomechanics.com/blog/topic/process-scale-up)
- [Extraction (7)](https://blog.sonomechanics.com/blog/topic/extraction)
- [Ultrasonic Degassing (7)](https://blog.sonomechanics.com/blog/topic/ultrasonic-degassing)
- [Theory of Ultrasonic Processing (6)](https://blog.sonomechanics.com/blog/topic/theory-of-ultrasonic-processing)
- [Wet Milling and Dispersing (4)](https://blog.sonomechanics.com/blog/topic/wet-milling-and-dispersing)
- [Deaeration (3)](https://blog.sonomechanics.com/blog/topic/deaeration)
- [Liquid Degassing (3)](https://blog.sonomechanics.com/blog/topic/liquid-degassing)
- [Cavitation (1)](https://blog.sonomechanics.com/blog/topic/cavitation)
- [Ultrasonic Transducer (1)](https://blog.sonomechanics.com/blog/topic/ultrasonic-transducer)
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#### About Us
Industrial Sonomechanics is a R&D, equipment design and process consulting firm, specializing in high-power ultrasonic technology for liquid treatment. Our mission is to help businesses implement their ultrasound-assisted processes on lab, pilot and industrial scales.
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