Oil-in-water emulsions with nano-sized droplets (nanoemulsions) are widely used in the pharmaceutical industry, for example, as an intravenous source of fatty acids when oral nutrition is disadvantageous or as bioactive compound carriers (e.g. drugs, vaccines). Pharmaceutical nanoemulsions can be administered by almost all available routes including parenteral, ocular, nasal, oral, topical, and even aerosolization to the lungs. There are currently over a dozen commercially available drugs encapsulated into nanoemulsions. Small oil droplet sizes and the associated stability of these products are critically important.
Ultrasonic Production of Pharmaceutical Emulsions
[fa icon="calendar'] Aug 24, 2015 12:56:00 AM / by Alexey Peshkovsky, Ph.D. posted in Emulsion-based Products
Advantages of Ultrasound for Producing Emulsion Fuels
[fa icon="calendar'] Aug 1, 2015 8:38:00 AM / by Alexey Peshkovsky, Ph.D. posted in Emulsion-based Products
Combustion equipment (e.g., diesel engines, power boilers) emits significant amounts of hazardous gasses, such as Nitrous Oxides (NOx), hydrocarbons (HC), carbon monoxide (CO), carbon dioxide (CO2) as well as particulate matter (PM) and black smoke. Due to the widespread use of this equipment, the resulting damage to human health and the environment is tremendous. Adding 5 – 25% of water to the base fuel, such as diesel or kerosene, in the form of a very fine emulsion (nanoemulsion) significantly reduces these harmful emissions.
Scaling Up the Production of Stable Emulsion-Based Products
[fa icon="calendar'] May 28, 2015 2:04:00 PM / by Alexey Peshkovsky, Ph.D. posted in Emulsion-based Products, Process Scale-up
Are you able to make stable emulsions in the lab, but have trouble replicating the same result in the production environment? Scaling up an emulsification process is frequently even more challenging than succeeding at its lab optimization. In most cases, the post-scale-up loss of product stability is caused by the inability of industrial liquid processors to provide the same intensity of shear forces as was implemented during the research phase, which is why choosing the right production-scale equipment is fundamental.
Achieving Stability of Oil-in-Water and Water-in-Oil Emulsion Products
[fa icon="calendar'] May 9, 2015 4:38:00 PM / by Alexey Peshkovsky, Ph.D. posted in Emulsion-based Products
Do you need to make a product that comprises a homogeneous mixture of oil and water? Is stability of this product a major concern? If so, you are not alone. One of the biggest challenges faced by product developers and process engineers in a wide variety of industries is achieving long-term stability of products based on combinations of oil and water.
ISM's Ultrasonic Technology Development Achievements During 2014
[fa icon="calendar'] Feb 26, 2015 12:22:00 AM / by Alexey Peshkovsky, Ph.D. posted in General Announcements