---
title: Sonomechanics Blog | Alexey Peshkovsky, Ph.D.
description: Dr. Alexey Peshkovsky is the Founder, President, and Chief Scientific Officer of Industrial Sonomechanics. He holds a B.A. in Chemistry from the University of Pennsylvania and a Ph.D. in Physical Chemistry from Columbia University. With more than 30 years of experience as a researcher, entrepreneur, product developer, and scientific director, his work has focused primarily on the design of ultrasonic instrumentation and the development of ultrasonic processes for a broad range of industrial applications. Dr. Peshkovsky is the lead author of an extensive body of scientific work, including journal publications, patents, conference presentations, and books.
---

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# Sonomechanics Blog

## Alexey Peshkovsky, Ph.D.

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Dr. Alexey Peshkovsky is the Founder, President, and Chief Scientific Officer of Industrial Sonomechanics. He holds a B.A. in Chemistry from the University of Pennsylvania and a Ph.D. in Physical Chemistry from Columbia University. With more than 30 years of experience as a researcher, entrepreneur, product developer, and scientific director, his work has focused primarily on the design of ultrasonic instrumentation and the development of ultrasonic processes for a broad range of industrial applications. Dr. Peshkovsky is the lead author of an extensive body of scientific work, including journal publications, patents, conference presentations, and books.

Find me on:

[\[fa icon="linkedin-square"\]](https://www.linkedin.com/pub/alexey-peshkovsky/15/692/1b1)

## Recent Posts

[![](https://blog.sonomechanics.com/hubfs/SONOMECHANICS%20INSTAGRAM%20POSTS%20(11)-2.jpg)](https://blog.sonomechanics.com/blog/water-cooled-piezoelectric-ultrasonic-transducers-for-continuous-industrial-processing)

## [Water-Cooled Piezoelectric Ultrasonic Transducers for Continuous Industrial Processing](https://blog.sonomechanics.com/blog/water-cooled-piezoelectric-ultrasonic-transducers-for-continuous-industrial-processing)

 \[fa icon="calendar'\] Sep 29, 2026, 3:57:58 PM / by [Alexey Peshkovsky, Ph.D.](https://blog.sonomechanics.com/blog/author/alexey-peshkovsky-ph-d) posted in [Ultrasonic Transducer](https://blog.sonomechanics.com/blog/topic/ultrasonic-transducer)

[\[fa icon="comment"\] 0 Comments](https://blog.sonomechanics.com/blog/water-cooled-piezoelectric-ultrasonic-transducers-for-continuous-industrial-processing#comments-listing)

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At industrial power levels, an ultrasonic transducer must manage the heat generated in it during electrical-to-mechanical energy conversion. If the heat cannot be removed continuously, the transducer’s operating time and production capacity will be limited. ISM developed its patented [SWCT](https://www.sonomechanics.com/water-cooled-transducers/)-series sealed water-cooled piezoelectric transducers to support continuous high-power operation while protecting high-voltage internal components from humidity and potentially flammable process vapors.

[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/water-cooled-piezoelectric-ultrasonic-transducers-for-continuous-industrial-processing)

[![](https://blog.sonomechanics.com/hubfs/2020-04-19_174531.jpg)](https://blog.sonomechanics.com/blog/vaccine-and-antiviral-drug-production-with-ism-ultrasonic-processors)

## [Vaccine and Antiviral Drug Production with ISM Ultrasonic Processors](https://blog.sonomechanics.com/blog/vaccine-and-antiviral-drug-production-with-ism-ultrasonic-processors)

 \[fa icon="calendar'\] Apr 28, 2020, 10:40:21 AM / by [Alexey Peshkovsky, Ph.D.](https://blog.sonomechanics.com/blog/author/alexey-peshkovsky-ph-d) posted in [Emulsion-based Products](https://blog.sonomechanics.com/blog/topic/emulsion-based-products), [Process Scale-up](https://blog.sonomechanics.com/blog/topic/process-scale-up), [Extraction](https://blog.sonomechanics.com/blog/topic/extraction)

[\[fa icon="comment"\] 2 Comments](https://blog.sonomechanics.com/blog/vaccine-and-antiviral-drug-production-with-ism-ultrasonic-processors#comments-listing)

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Recent years have seen major breakthroughs in how vaccines and antiviral drugs are formulated and manufactured. Nanoemulsions and liposomes are now widely used as vaccine and drug carriers because they can easily incorporate lipophilic (in the case of nanoemulsions) and hydrophilic (in the case of liposomes) bioactive compounds, stabilize substances that otherwise undergo hydrolysis, and significantly reduce side effects of potent drugs. For the past 14 years, Industrial Sonomechanics ([ISM](http://www.sonomechanics.com)) has been conducting R&D and supplying its scalable ultrasonic [technology](https://sonomechanics.com/barbell-horn-ultrasonic-technology/) to many companies in this field, including those using it in ultrasonic vaccine production and, more recently, in the development of SARS-CoV-2 (novel coronavirus) vaccines and/or treatments of the associated COVID-19 disease. This article describes some of the challenges faced by commercial-scale manufacturers of vaccines and antiviral medications and explains how our technology contributes to overcoming them.  

[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/vaccine-and-antiviral-drug-production-with-ism-ultrasonic-processors)

[![](https://blog.sonomechanics.com/hubfs/d50%2c%20d95%20vs%20STB-CBD%20ratio%2c%20updated.jpg)](https://blog.sonomechanics.com/blog/6-frequently-asked-questions-about-nanostabilizer)

## [6 Frequently Asked Questions About All-In-One NanoStabilizer®-LT](https://blog.sonomechanics.com/blog/6-frequently-asked-questions-about-nanostabilizer)

 \[fa icon="calendar'\] Feb 3, 2020, 11:48:04 AM / by [Alexey Peshkovsky, Ph.D.](https://blog.sonomechanics.com/blog/author/alexey-peshkovsky-ph-d) posted in [Emulsion-based Products](https://blog.sonomechanics.com/blog/topic/emulsion-based-products), [Medical Cannabis](https://blog.sonomechanics.com/blog/topic/medical-cannabis)

[\[fa icon="comment"\] 4 Comments](https://blog.sonomechanics.com/blog/6-frequently-asked-questions-about-nanostabilizer#comments-listing)

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For the past two years, many businesses have been using our all-in-one **[NanoStabilizer®-LT](https://blog.sonomechanics.com/blog/nanostabilizer-for-producing-water-soluble-cannabis-extracts)** to convert their cannabis extracts and other hydrophobic bio-actives into water-compatible, stable, translucent nanoemulsions. Most commonly, the conversion is done in order to enhance the bioavailability and accelerate the onset of action of cannabinoids and to infuse beverages without making them cloudy. Designed to work with Industrial Sonomechanics ultrasonic liquid [processors](https://drive.google.com/open?id=1dFLsc4nVSGbxSW8izJZuJpXZ9OkgOc_5), NanoStabilizer®-LT requires no formulation development experience and is compatible with a wide range of bio-actives, including most types of cannabis extracts and isolates, pharmaceutical ingredients, vitamins, essential oils, terpenes, etc. In this post, I provide answers to some of the most commonly asked questions about this popular product.

[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/6-frequently-asked-questions-about-nanostabilizer)

[![](https://blog.sonomechanics.com/hubfs/Images_for_Blog_Posts/Cannabis_blogs/Sterilizing%20a%20Nanoemulsion%20by%20In-line%20Filtration.jpg)](https://blog.sonomechanics.com/blog/should-i-filter-my-water-soluble-cannabis-nanoemulsion)

## [Why Sterile-Filter Water-Compatible Cannabis Extract Nanoemulsions?](https://blog.sonomechanics.com/blog/should-i-filter-my-water-soluble-cannabis-nanoemulsion)

 \[fa icon="calendar'\] Dec 3, 2018, 10:23:58 AM / by [Alexey Peshkovsky, Ph.D.](https://blog.sonomechanics.com/blog/author/alexey-peshkovsky-ph-d) posted in [Emulsion-based Products](https://blog.sonomechanics.com/blog/topic/emulsion-based-products), [Medical Cannabis](https://blog.sonomechanics.com/blog/topic/medical-cannabis)

[\[fa icon="comment"\] 12 Comments](https://blog.sonomechanics.com/blog/should-i-filter-my-water-soluble-cannabis-nanoemulsion#comments-listing)

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Sterile filtration is an important post-processing step of ultrasonic nano-emulsification - a process that converts cannabis extracts and/or other hydrophobic bioactives into a water-compatible form. In this article, I will summarize the steps of the nano-emulsification process carried out with **[BHUT](https://www.youtube.com/watch?v=IAc-glwNAto)**-based ultrasonic equipment and **[NanoStabilizer®-LT](https://blog.sonomechanics.com/blog/nanostabilizer-for-producing-water-soluble-cannabis-extracts)**, list the main advantages of the resulting water-compatible nanoemulsions, and explain why sterile filtration is always necessary at the end. Answers to several FAQs will also be provided.

[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/should-i-filter-my-water-soluble-cannabis-nanoemulsion)

[![](https://blog.sonomechanics.com/hubfs/Woman%20drinking%20a%20beverage-135.png)](https://blog.sonomechanics.com/blog/managing-the-bitter-taste-of-cannabis-infused-beverages)

## [How to Manage the Bitter Taste of Cannabis-Infused Beverages](https://blog.sonomechanics.com/blog/managing-the-bitter-taste-of-cannabis-infused-beverages)

 \[fa icon="calendar'\] Sep 18, 2018, 9:00:00 AM / by [Alexey Peshkovsky, Ph.D.](https://blog.sonomechanics.com/blog/author/alexey-peshkovsky-ph-d) posted in [Emulsion-based Products](https://blog.sonomechanics.com/blog/topic/emulsion-based-products), [Medical Cannabis](https://blog.sonomechanics.com/blog/topic/medical-cannabis)

[\[fa icon="comment"\] 21 Comments](https://blog.sonomechanics.com/blog/managing-the-bitter-taste-of-cannabis-infused-beverages#comments-listing)

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We are frequently asked how to minimize the bitter taste of products made with cannabis extract nanoemulsions (a.k.a., water-soluble CBD and THC). Infusing beverages with CBD and/or THC-containing translucent nanoemulsions (ideally, averaging ~20 nanometers in droplet size diameter) offers a very convenient, discrete and effective consumption method. The infusion does not change the original appearance of the beverages while instantly enabling them to provide a very rapid onset of action and high bioavailability of cannabinoids as well as of any other incorporated active ingredients. With this pharmacokinetic profile, the experience a lot more similar to consuming an alcoholic beverage than a typical cannabis-containing edible, which provides a myriad of attractive options for the vendors and consumers. In many cases, however, the infusion results in a bitter taste, which can range in intensity from virtually undetectable to quite unpleasant and makes it important to understand and manage.

[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/managing-the-bitter-taste-of-cannabis-infused-beverages)

[![](https://blog.sonomechanics.com/hubfs/Images_for_Blog_Posts/Cannabis_blogs/cannabis%20nebulization%20-%20small.jpg)](https://blog.sonomechanics.com/blog/ways-to-consume-cannabis-how-nanoemulsions-can-help)

## [Ways to Consume Cannabis: How Water-Compatible Nanoemulsions Can Help](https://blog.sonomechanics.com/blog/ways-to-consume-cannabis-how-nanoemulsions-can-help)

 \[fa icon="calendar'\] Aug 20, 2017, 9:00:00 AM / by [Alexey Peshkovsky, Ph.D.](https://blog.sonomechanics.com/blog/author/alexey-peshkovsky-ph-d) posted in [Emulsion-based Products](https://blog.sonomechanics.com/blog/topic/emulsion-based-products), [Medical Cannabis](https://blog.sonomechanics.com/blog/topic/medical-cannabis)

[\[fa icon="comment"\] 11 Comments](https://blog.sonomechanics.com/blog/ways-to-consume-cannabis-how-nanoemulsions-can-help#comments-listing)

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There are many ways to administer medical and recreational cannabis, each with its own benefits and drawbacks. One common feature, however, is that only a certain (generally small) percentage of the consumed cannabinoid content, defined as "bioavailability", can be absorbed into the bloodstream with each method. This stems from the fact that cannabinoids are not water-soluble and, therefore, not readily compatible with the predominantly water-based human body. Water-soluble compounds such as ethanol, on the other hand, can be quickly and efficiently delivered to the bloodstream via a variety of alcoholic beverages, eliminating the need for other delivery methods. Wouldn't it be great if the same could be done with cannabis?

[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/ways-to-consume-cannabis-how-nanoemulsions-can-help)

[![](https://blog.sonomechanics.com/hubfs/Images_for_Blog_Posts/Cannabis_blogs/bioavalbility.jpg)](https://blog.sonomechanics.com/blog/the-role-of-carrier-oils-in-water-soluble-cbd-and-thc-formulations)

## [The Role of Carrier Oils in Water-Soluble CBD and THC Formulations](https://blog.sonomechanics.com/blog/the-role-of-carrier-oils-in-water-soluble-cbd-and-thc-formulations)

 \[fa icon="calendar'\] Jan 28, 2017, 11:37:28 AM / by [Alexey Peshkovsky, Ph.D.](https://blog.sonomechanics.com/blog/author/alexey-peshkovsky-ph-d) posted in [Emulsion-based Products](https://blog.sonomechanics.com/blog/topic/emulsion-based-products), [Medical Cannabis](https://blog.sonomechanics.com/blog/topic/medical-cannabis)

[\[fa icon="comment"\] 51 Comments](https://blog.sonomechanics.com/blog/the-role-of-carrier-oils-in-water-soluble-cbd-and-thc-formulations#comments-listing)

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This is a second article in the series on the principles of formulating water-compatible cannabis extracts and isolates, also known as water-soluble CBD and THC. The [**first article**](https://blog.sonomechanics.com/blog/water-soluble-cannabis-oil-microemulsion-liposomes-or-nanoemulsion) showed multiple advantages of *nanoemulsions* over the other two water-compatible formulation classes: *microemulsions* and *liposomes*. Here I will demonstrate the importance of using a carrier oil in your cannabis extract or isolate [**nanoemulsion**](https://blog.sonomechanics.com/blog/ultrasonic-production-of-nano-cannabinoids). I will also explain how to select the proper carrier oil among the available choices.

[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/the-role-of-carrier-oils-in-water-soluble-cbd-and-thc-formulations)

[![](https://blog.sonomechanics.com/hubfs/Images_for_Blog_Posts/Cannabis_blogs/water-soluble-extract-white-emulsion-1.2-1.jpg)](https://blog.sonomechanics.com/blog/water-soluble-cannabis-oil-microemulsion-liposomes-or-nanoemulsion)

## [Water-Soluble Cannabis Oils: Microemulsion, Liposomes or Nanoemulsion?](https://blog.sonomechanics.com/blog/water-soluble-cannabis-oil-microemulsion-liposomes-or-nanoemulsion)

 \[fa icon="calendar'\] Nov 24, 2016, 9:00:00 AM / by [Alexey Peshkovsky, Ph.D.](https://blog.sonomechanics.com/blog/author/alexey-peshkovsky-ph-d) posted in [Emulsion-based Products](https://blog.sonomechanics.com/blog/topic/emulsion-based-products), [Medical Cannabis](https://blog.sonomechanics.com/blog/topic/medical-cannabis)

[\[fa icon="comment"\] 94 Comments](https://blog.sonomechanics.com/blog/water-soluble-cannabis-oil-microemulsion-liposomes-or-nanoemulsion#comments-listing)

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Industrial Sonomechanics is launching a series of blog posts dedicated to describing the main principles of developing water-compatible cannabis extract formulations, also known as water-soluble CBD and THC. As explained in our earlier<https://blog.sonomechanics.com/blog/water-soluble-cbd>**[blog post](https://blog.sonomechanics.com/blog/water-soluble-cbd)**, since medical marijuana extracts are oils and, as such, not soluble in water, they have to be specially formulated in order to become water-compatible and acquire the *appearance* of being water-soluble. There are three formulation classes that can provide this property: *microemulsions, liposomes* and *nanoemulsions*.  

[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/water-soluble-cannabis-oil-microemulsion-liposomes-or-nanoemulsion)

[![](https://blog.sonomechanics.com/hubfs/Images_for_Blog_Posts/Cannabis_blogs/medicinal-cannabis-with-extract-oil.jpg)](https://blog.sonomechanics.com/blog/cannabis-concentrates-medical-significance-and-extraction-methods)

## [Cannabis Concentrates: Medical Significance and Extraction Methods](https://blog.sonomechanics.com/blog/cannabis-concentrates-medical-significance-and-extraction-methods)

 \[fa icon="calendar'\] Oct 22, 2016, 8:00:00 AM / by [Alexey Peshkovsky, Ph.D.](https://blog.sonomechanics.com/blog/author/alexey-peshkovsky-ph-d) posted in [Medical Cannabis](https://blog.sonomechanics.com/blog/topic/medical-cannabis), [Extraction](https://blog.sonomechanics.com/blog/topic/extraction)

[\[fa icon="comment"\] 25 Comments](https://blog.sonomechanics.com/blog/cannabis-concentrates-medical-significance-and-extraction-methods#comments-listing)

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The cannabis (marijuana, hemp) plant has been used for medicinal purposes for millennia.  In addition to terpenes and flavonoids, over 100 types of therapeutically active compounds known as *cannabinoids* have been identified in these plants \[1\]. The two most important and well-known cannabinoids are tetrahydrocannabinol (THC) and cannabidiol (CBD) \[2\]. Cannabinoids have the ability to directly and/or indirectly affect receptors in our cells because they mimic *endocannabinoids* produced by our own bodies endogenously, for example, in response to injury \[3\].

[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/cannabis-concentrates-medical-significance-and-extraction-methods)

[![](https://blog.sonomechanics.com/hubfs/Processes_and_tests/Cannabis/cbd-oil-tincture.jpg)](https://blog.sonomechanics.com/blog/water-soluble-cbd)

## [Can CBD or THC be Made Water-Soluble?](https://blog.sonomechanics.com/blog/water-soluble-cbd)

 \[fa icon="calendar'\] Jul 3, 2016, 10:11:12 AM / by [Alexey Peshkovsky, Ph.D.](https://blog.sonomechanics.com/blog/author/alexey-peshkovsky-ph-d) posted in [Emulsion-based Products](https://blog.sonomechanics.com/blog/topic/emulsion-based-products), [Medical Cannabis](https://blog.sonomechanics.com/blog/topic/medical-cannabis)

[\[fa icon="comment"\] 91 Comments](https://blog.sonomechanics.com/blog/water-soluble-cbd#comments-listing)

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Cannabinoids (CBD, THC, etc.) are hydrophobic (water-hating) oily substances and, as such, not water-**soluble**. They can, however, be formulated to be water-**compatible** and **appear** water-soluble.

The term "water-soluble CBD" has lately been extensively used throughout the medical cannabis industry. "Water-soluble" means able to homogeneously incorporate into water by separating into molecules or ions (**dissolve** like sugar, alcohol or salt). Oily substances, however, are repelled by water, which forces them to stay separate from it.

[Read More \[fa icon="long-arrow-right"\]](https://blog.sonomechanics.com/blog/water-soluble-cbd)

[All posts](https://blog.sonomechanics.com/blog/all) [Next \[fa icon="angle-double-right"\]](https://blog.sonomechanics.com/blog/author/alexey-peshkovsky-ph-d/page/2)

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- [Emulsion-based Products (39)](https://blog.sonomechanics.com/blog/topic/emulsion-based-products)
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- [Extraction (7)](https://blog.sonomechanics.com/blog/topic/extraction)
- [Ultrasonic Degassing (7)](https://blog.sonomechanics.com/blog/topic/ultrasonic-degassing)
- [Theory of Ultrasonic Processing (6)](https://blog.sonomechanics.com/blog/topic/theory-of-ultrasonic-processing)
- [Wet Milling and Dispersing (4)](https://blog.sonomechanics.com/blog/topic/wet-milling-and-dispersing)
- [Deaeration (3)](https://blog.sonomechanics.com/blog/topic/deaeration)
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