One of the primary concerns when formulating oil-in-water (O/W) nanoemulsions is the stability of the finished product. Destabilization of an O/W nanoemulsion can occur due to several physical, chemical or biological processes that deteriorate its quality over time. Understanding and avoiding these processes is paramount to ensuring that products based on cannabis extract nanoemulsions (a.k.a. "water-soluble" CBD and THC) have a long and predictable shelf-life. In this post, common nanoemulsion destabilization pathways will be described, along with the most effective strategies to avoid them.
We are happy to announce that Industrial Sonomechanics (ISM) will participate in the 2019 USA CBD Expo in Miami Beach, FL. The event will take place on August 2nd - 4th, 2019, at the Miami Beach Convention Center. At the Expo, ISM's President and Chief Scientific Officer, Dr. Alexey Peshkovsky, will give a talk on how to design and manufacture translucent, permanently stable, fully water-compatible cannabinoid nanoemulsions (aka. water-soluble CBD or THC), which are efficiently absorbed by the body via many convenient administration routes (e.g., as beverages, edibles and topicals).
We are happy to announce that Industrial Sonomechanics (ISM) will participate in the 2019 Cannabis Drinks Expo in San Francisco, CA. The event will take place on July 25th, 2019, at the South San Francisco Conference Center. At the Expo, ISM's President and Chief Scientific Officer, Dr. Alexey Peshkovsky, will give a talk on the benefits, production methodologies, characteristics and administration methods of cannabis extract nanoemulsions (also known as water-soluble CBD and THC), mainly targeting the infused beverage industry. Some of our technology aimed at enabling companies to produce their own cannabis extract and other bio-active ingredient nanoemulsions will also be presented.
We are growing, so we are moving!
On May 1st, 2019, Industrial Sonomechanics (ISM) will relocate to a much larger facility at 7440 SW 50th Terrace #110, Miami, FL 33155. Our phone numbers will still be the same: 646-580-4676 (for sales and technical support) and 786-332-3652 (for general inquiries).
Last October, Dr. Alexey Peshkovsky, President & Chief Scientific Officer of Industrial Sonomechanics, presented a talk entitled Why and How to Make Cannabis Extracts "Water-Soluble" at Marijuana for Medical Professionals conference in Denver, Colorado. A variety of topics were covered, including the development, manufacture and administration methods of translucent cannabis extract nanoemulsions, also known as water-soluble CBD and THC.
We are happy to announce that Industrial Sonomechanics (ISM) will participate in the 2019 MJBizConNEXT in New Orleans, LA. The conference will take place on June12th - 14th, 2019, at the Ernest N. Morial Convention Center. If you are interested in making cannabis oil nanoemulsions, also known as water-soluble CBD or THC, please come by and see our ultrasonic equipment and NanoStabilizer™ at booth #634!
Sterile filtration is an important post-processing step of ultrasonic nano-emulsification - a process that converts cannabis extracts and/or other hydrophobic bioactives into a water-compatible form. In this article, I will summarize the steps of the nano-emulsification process carried out with BHUT-based ultrasonic equipment and NanoStabilizer®, list the main advantages of the resulting water-compatible nanoemulsions, and explain why sterile filtration is always necessary at the end. Answers to several FAQs will also be provided.
We are excited to announce that ISM will participate in 2018 Marijuana for Medical Professionals conference in Denver, CO, taking place on October 14 - 16, 2018, at the Marriott Hotel Denver Tech Center.
At the conference, ISM President and Chief Scientific Officer, Dr. Alexey Peshkovsky, will be giving a talk, entitled "How and Why to Make Cannabis "Water-Soluble"."
If you are interested in learning about translucent, water-compatible nanoemulsions of cannabis extracts that can be infused into beverages, edibles and topicals, resulting in enhanced bioavailability and shortened onset of therapeutic action, please come see Dr. Peshkovsky's presentation!
We are frequently asked how to minimize the bitter taste of products made with cannabis extract nanoemulsions (a.k.a., water-soluble CBD and THC). Infusing beverages with CBD and/or THC-containing translucent nanoemulsions (ideally, averaging ~20 nanometers in droplet size diameter) offers a very convenient, discrete and effective consumption method. The infusion does not change the original appearance of the beverages while instantly enabling them to provide a very rapid onset of action and high bioavailability of cannabinoids as well as of any other incorporated active ingredients. With this pharmacokinetic profile, the experience a lot more similar to consuming an alcoholic beverage than a typical cannabis-containing edible, which provides a myriad of attractive options for the vendors and consumers. In many cases, however, the infusion results in a bitter taste, which can range in intensity from virtually undetectable to quite unpleasant and makes it important to understand and manage.