Recent years have seen major breakthroughs in how vaccines and antiviral drugs are formulated and manufactured. Nanoemulsions and liposomes are now widely used as vaccine and drug carriers because they can easily incorporate lipophilic (in the case of nanoemulsions) and hydrophilic (in the case of liposomes) bioactive compounds, stabilize substances that otherwise undergo hydrolysis, and significantly reduce side effects of potent drugs. For the past 14 years, Industrial Sonomechanics (ISM) has been conducting R&D and supplying its scalable ultrasonic technology to many companies in this field, including those using it in ultrasonic vaccine production and, more recently, in the development of SARS-CoV-
For the past two years, many businesses have been using our all-in-one NanoStabilizer®-LT to convert their cannabis extracts and other hydrophobic bio-actives into water-compatible, stable, translucent nanoemulsions. Most commonly, the conversion is done in order to enhance the bioavailability and accelerate the onset of action of cannabinoids and to infuse beverages without making them cloudy. Designed to work with Industrial Sonomechanics ultrasonic liquid processors, NanoStabilizer®-LT requires no formulation development experience and is compatible with a wide range of bio-actives, including most types of cannabis extracts and isolates, pharmaceutical ingredients, vitamins, essential oils, terpenes, etc. In this post, I provide answers to some of the most commonly asked questions about this popular product.
We are happy to announce that the recording of Dr. Alexey Peshkovsky's 2019 Cannabis Drinks Expo keynote presentation is now ready. In his talk, entitled "Water-compatible cannabis extract nanoemulsions: benefits, formulation development and production methodology", ISM President & Chief Scientific Officer covered several topics critical to the cannabis-infused beverage industry.
One of the primary concerns when formulating oil-in-water (O/W) nanoemulsions is the stability of the finished product. Destabilization of an O/W nanoemulsion can occur due to several physical, chemical or biological processes that deteriorate its quality over time. Understanding and avoiding these processes is paramount to ensuring that products based on cannabis extract nanoemulsions (a.k.a. "water-soluble" CBD and THC) have a long and predictable shelf-life. In this post, common nanoemulsion destabilization pathways will be described, along with the most effective strategies to avoid them.
We are happy to announce that Industrial Sonomechanics (ISM) will participate in the 2019 USA CBD Expo in Miami Beach, FL. The event will take place on August 2nd - 4th, 2019, at the Miami Beach Convention Center. At the Expo, ISM's President and Chief Scientific Officer, Dr. Alexey Peshkovsky, will give a talk on how to design and manufacture translucent, permanently stable, fully water-compatible cannabinoid nanoemulsions (aka. water-soluble CBD or THC), which are efficiently absorbed by the body via many convenient administration routes (e.g., as beverages, edibles and topicals).
We are happy to announce that Industrial Sonomechanics (ISM) will participate in the 2019 Cannabis Drinks Expo in San Francisco, CA. The event will take place on July 25th, 2019, at the South San Francisco Conference Center. At the Expo, ISM's President and Chief Scientific Officer, Dr. Alexey Peshkovsky, will give a talk on the benefits, production methodologies, characteristics and administration methods of cannabis extract nanoemulsions (also known as water-soluble CBD and THC), mainly targeting the infused beverage industry. Some of our technology aimed at enabling companies to produce their own cannabis extract and other bio-active ingredient nanoemulsions will also be presented.
We are growing, so we are moving!
On May 1st, 2019, Industrial Sonomechanics (ISM) will relocate to a much larger facility at 7440 SW 50th Terrace #110, Miami, FL 33155. Our phone numbers will still be the same: 646-580-4676 (for sales and technical support) and 786-332-3652 (for general inquiries).