Sonomechanics Blog

Benefits include significantly faster throughput, less downtime, and lower total cost of ownership.

Industrial Sonomechanics, LLC (ISM) is happy to announce the commercial availability of several new large-capacity in-line filtration products, which increase the efficiency of the nanoemulsion production process and lower the associated cost. 

Filtering is key to nanoemulsion production

Filtration is a necessary post-processing step of ultrasonic nano-emulsification—a process that converts cannabis extracts and/or other hydrophobic bioactives into a water-compatible form. This new integrated unit removes microorganisms (sterilization), dust, titanium particles, and any leftover plant matter while making filtration convenient and highly scalable.

At 1:00 pm EST on June 28th, 2022, please join us for a YouTube podcast with a live Q&A session. This event, entitled "Make and Measure the Potency of Cannabis Extract Nanoemulsions", is a collaboration project between Industrial Sonomechanics (ISM) and Orange Photonics, where Dr. Alexey Peshkovsky (ISM) and Mr. Dylan Wilks (Orange Photonics) will discuss:

1. ISM's ultrasonic technology and NanoStabilizer® formulations used to produce water-soluble cannabis extract nanoemulsions in the forms of translucent liquids, powders, and quick-disintegrating tablets.

2. Principles of Orange Photonics' Light Lab liquid chromatography technology used to measure the potency of liquid and powdered water-soluble cannabis extract nanoemulsions, including detection limits for various cannabinoids.

3. Best ways to prepare samples comprising various nanoemulsion types for accurate cannabinoid content analysis.

4. Typical reasons for and ways to avoid inconsistent or diminishing cannabinoid potency results in nanoemulsions.

5. Benefits of having a Light Lab cannabis analyzer in-house.

We will be chatting with our viewers throughout the presentation. If interested, please join the conversation at 1:00 pm EST on June 28th, 2022!

Nutraceuticals World recently interviewed our President and Chief Scientific Officer, Dr. Alexey Peshkovsky, for an article covering the topic of nanoemulsion innovations in hemp and cannabis product development.

To read the full story and learn more about what we have been working on in the nutraceuticals space please follow this link. 

The production of water-soluble nanoemulsions has been a growing segment of the cannabis and nutraceuticals markets. These products manifest themselves in terms of accelerated onset time, high bioavailability, consistent effect, and precise and reproducible therapeutic dosing, as shown by recent pre-clinical studies.

In March of this year, Industrial Sonomechanics (ISM) hosted a webinar, entitled "Water-Compatible Nanoemulsions: The Battle of Formulations", presented by ISM's President and Chief Scientific Officer, Dr. Alexey Peshkovsky. The video recording of this event has been posted on our YouTube channel.

The webinar generated over 100 questions, some of which were addressed by Alexey during the event. The answers to the remaining questions are provided below. If you have any additional questions, please do not hesitate to contact us or leave a comment below. 

If you want to produce cannabis extract nanoemulsions in water-soluble powder form, look no further than Industrial Sonomechanics’ (ISM) new offering — the tasteless, all-natural and organic All-In-One NanoStabilizer®-LSO formulation. Building on the tremendous success of our All-In-One NanoStabilizer®-LT introduced in 2018, the ISM team is at it again as it pushes the envelope of innovation in the production of water-compatible nanoemulsions.
Over the past year, we have experienced significant interest from customers for a flexible, yet cost-effective method to make a finished nanoemulsion in powder form that reconstitutes back into a liquid nanoemulsion upon contact with water. The creation of NanoStabilizer®-LSO now makes it possible for companies to produce such water-soluble powders from their active ingredients (CBD, Delta 9 THC, Delta 8 THC, essential oils, vitamins, nutraceuticals, etc.), bringing their branding and application ideas to life.

The video recording of our recent webinar, "Analysis, Optimization and Production of Translucent Nanoemulsions", presented by Industrial Sonomechanics' R&D Scientist, Mr. Shlomo Leibtag, and Micromeritics' Global Technical Training and Support Manager, Mr. Jack G. Saad, is now ready. The webinar had over 200 registered participants and generated close to 100 questions. Some of these questions were addressed by Shlomo and Jack during the event. The answers to the rest are provided below. If you have any additional questions, please do not hesitate to contact us or leave a comment below. 

Recent years have seen major breakthroughs in how vaccines and antiviral drugs are formulated and manufactured. Nanoemulsions and liposomes are now widely used as vaccine and drug carriers because they can easily incorporate lipophilic (in the case of nanoemulsions) and hydrophilic (in the case of liposomes) bioactive compounds, stabilize substances that otherwise undergo hydrolysis, and significantly reduce side effects of potent drugs. For the past 14 years, Industrial Sonomechanics (ISM) has been conducting R&D and supplying its scalable ultrasonic technology to many companies in this field, including those using it in ultrasonic vaccine production and, more recently, in the development of SARS-CoV-2 (novel coronavirus) vaccines and/or treatments of the associated COVID-19 disease. This article describes some of the challenges faced by commercial-scale manufacturers of vaccines and antiviral medications and explains how our technology contributes to overcoming them.  

For the past two years, many businesses have been using our all-in-one NanoStabilizer®-LT to convert their cannabis extracts and other hydrophobic bio-actives into water-compatible, stable, translucent nanoemulsions. Most commonly, the conversion is done in order to enhance the bioavailability and accelerate the onset of action of cannabinoids and to infuse beverages without making them cloudy. Designed to work with Industrial Sonomechanics ultrasonic liquid processors, NanoStabilizer®-LT requires no formulation development experience and is compatible with a wide range of bio-actives, including most types of cannabis extracts and isolates, pharmaceutical ingredients, vitamins, essential oils, terpenes, etc. In this post, I provide answers to some of the most commonly asked questions about this popular product.